What is NDC 66220-315?

66220-315 is the product NDC for Vibativ (telavancin hydrochloride), Telavancin hydrochloride 15 mg/mL injection, powder, lyophilized, for solution, listed with the FDA by Cumberland Pharmaceuticals Inc.. It has 3 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Vibativ (Telavancin hydrochloride).

Cumberland Pharmaceuticals Inc., NDC labeler code 66220. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Vibativ?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Vibativ NDC 66220-315 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)66220-315Labeler and product segments. Claims need a package NDC.

Product NDC at billing width66220-0315Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
66220-315-11	6622003151166220031511	1 VIAL, SINGLE-DOSE in 1 CARTON (66220-315-11) / 50 mL in 1 VIAL, SINGLE-DOSEMarketed from Jan 1, 2021
66220-315-22	6622003152266220031522	12 VIAL, SINGLE-DOSE in 1 CARTON (66220-315-22) / 50 mL in 1 VIAL, SINGLE-DOSEMarketed from Jan 1, 2021
66220-315-44	6622003154466220031544	4 VIAL, SINGLE-DOSE in 1 CARTON (66220-315-44) / 50 mL in 1 VIAL, SINGLE-DOSEMarketed from Dec 1, 2023

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Vibativ
Generic name (nonproprietary): telavancin hydrochloride
Active ingredients: Telavancin hydrochloride — 15 mg/mL
Dosage form: Injection, Powder, Lyophilized, For solution
Route: Intravenous
Labeler: Cumberland Pharmaceuticals Inc.NDC labeler code 66220
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 022110
Marketing start: Jan 1, 2021
Listing expires: Dec 31, 2026
Other FDA classes: Lipoglycopeptides (EXT)
Identifiers: Product ID 66220-315_7664f8a4-33c4-4f30-998e-86333640c44dSPL ID 7664f8a4-33c4-4f30-998e-86333640c44dSPL set ID 5359b759-db7c-4672-9e8a-59c93869bd91RxCUI 1728082, 1728085UNII 0701472ZG0
Pharmacologic class: Lipoglycopeptide Antibacterial

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N466220031511 followed by a unit qualifier and the quantity

Package 66220-0315-11. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 19, 2025. This label includes a boxed warning.

Indications (excerpt from the label)

VIBATIV is a lipoglycopeptide antibacterial drug indicated for the treatment of the following infections in adult patients caused by designated susceptible bacteria: Complicated skin and skin structure infections (cSSSI) ( 1.1 ) Hospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) caused by susceptible isolates of Staphylococcus aureus . VIBATIV should be reserved for use when alternative treatments are not suitable. ( 1.2 ) To reduce the development of drug-resistant bacteria and maintain the effectiveness of VIBATIV and other antibacterial drugs VIBATIV should only be used to treat or prevent infections that are proven or strongly suspected to be caused by bacteria. …

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 66220-315

What is NDC 66220-315?: 66220-315 is the product NDC for Vibativ (telavancin hydrochloride), Telavancin hydrochloride 15 mg/mL injection, powder, lyophilized, for solution, listed with the FDA by Cumberland Pharmaceuticals Inc.. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Vibativ (Telavancin hydrochloride).
What is the active ingredient?: Telavancin hydrochloride.
Who is the labeler?: Cumberland Pharmaceuticals Inc., NDC labeler code 66220. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Vibativ?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Vibativ (Telavancin hydrochloride) NDC 66220-315