NDC codes

FDA NDC Directory
Product NDC (as listed)66794-021Labeler and product segments. Claims need a package NDC.
Product NDC at billing width66794-0021Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
66794-021-2566794002125250 mL in 1 BOTTLE, GLASS (66794-021-25)Marketed from Jan 31, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Desflurane
Generic name (nonproprietary)
desflurane
Active ingredients
Desflurane — 250 mL/250mL
Dosage form
Liquid
Route
Respiratory (Inhalation)
Product type
Prescription drug
Marketing category
Unapproved drug (other)
Marketing start
Listing expires
Other FDA classes
General Anesthesia (Physiologic effect)
Identifiers
Product ID 66794-021_37c2af0f-10b2-c8a1-e063-6394a90a070dSPL ID 37c2af0f-10b2-c8a1-e063-6394a90a070dSPL set ID 80883017-6797-43b2-a500-36843e7e1affRxCUI 562366UNII CRS35BZ94Q
Pharmacologic class
General Anesthetic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N466794002125 followed by a unit qualifier and the quantity

Package 66794-0021-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

Desflurane, USP, liquid for inhalation a general anesthetic, is an inhalation agent indicated: • for induction and/or maintenance of anesthesia in adults ( 1.1 ) • for maintenance of anesthesia in pediatric patients following induction with agents other than Desflurane, USP, liquid for inhalation and intubation. 1.1 Induction of Anesthesia Desflurane USP, liquid for inhalation is indicated as an inhalation agent for induction of anesthesia for inpatient and outpatient surgery in adults. Desflurane, USP, liquid for inhalation is contraindicated as an inhalation agent for the induction of anesthesia in pediatric patients because of a high incidence of moderate to severe upper airway adverse ev…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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