What is NDC 72189-258?

72189-258 is the product NDC for Rizatriptan Benzoate, Rizatriptan benzoate 10 mg/1 tablet, listed with the FDA by direct rx. It has 2 package NDCs, shown above in 10- and 11-digit form.

direct rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Rizatriptan Benzoate?

56 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Rizatriptan Benzoate NDC 72189-258

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-258Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0258Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-258-12	7218902581272189025812	12 TABLET in 1 BOTTLE (72189-258-12)Marketed from Aug 10, 2021
72189-258-18	7218902581872189025818	18 TABLET in 1 BLISTER PACK (72189-258-18)Marketed from Aug 10, 2021

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Rizatriptan Benzoate
Generic name (nonproprietary): rizatriptan benzoate
Active ingredients: Rizatriptan benzoate — 10 mg/1
Dosage form: Tablet
Route: Oral
Labeler: direct rxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 202490
Marketing start: Aug 10, 2021
Listing expires: Dec 31, 2027
Other FDA classes: Serotonin 1b Receptor Agonists (Mechanism)Serotonin 1d Receptor Agonists (Mechanism)
Identifiers: Product ID 72189-258_4c4bf9d8-0622-f896-e063-6294a90a3674SPL ID 4c4bf9d8-0622-f896-e063-6294a90a3674SPL set ID b3d981bc-3c9e-8a9e-e053-2995a90a8f65RxCUI 312840, 314209UNII WR978S7QHH
Pharmacologic class: Serotonin-1b and Serotonin-1d Receptor Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189025812 followed by a unit qualifier and the quantity

Package 72189-0258-12. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 5, 2026.

Indications (excerpt from the label)

Rizatriptan benzoate tablets are indicated for the acute treatment of migraine with or without aura in adults and in pediatric patients 6 to 17 years old. Information related to usage of rizatriptan benzoate in pediatric patients (6 to 17 years old) is approved for Merck & Co., Inc.’s Rizatriptan Benzoate Tablets. However, due to Merck & Co., Inc.’s marketing exclusivity rights, this drug product is not labeled with that pediatric patient (6 to 17 years old) usage information. Limitations of Use Rizatriptan benzoate tablets should only be used where a clear diagnosis of migraine has been established. If a patient has no response for the first migraine attack treated with rizatriptan benzoate…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-258

What is NDC 72189-258?: 72189-258 is the product NDC for Rizatriptan Benzoate, Rizatriptan benzoate 10 mg/1 tablet, listed with the FDA by direct rx. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Rizatriptan Benzoate.
What is the active ingredient?: Rizatriptan benzoate.
Who is the labeler?: direct rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Rizatriptan Benzoate?: 56 other product NDCs are listed under this name. See all Rizatriptan Benzoate NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Rizatriptan Benzoate NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	Tablet, Orally disintegratingOral	Advanced Rx of Tennessee, LLC	80425-0535	80425-0535-01
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	Tablet, Orally disintegratingOral	REMEDYREPACK INC.	70518-4362	70518-4362-00
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Direct_Rx	72189-512	72189-0512-18
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	Tablet, Film coatedOral	Direct_Rx	72189-447	72189-0447-18
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Direct Rx	72189-316	72189-0316-18
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	DIRECT RX	61919-656	61919-0656-12
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	DIRECT RX	61919-394	61919-0394-18
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	Tablet, Orally disintegratingOral	Unichem Pharmaceuticals (USA), Inc.	29300-268	29300-0268-2129300-0268-8129300-0268-91
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	Tablet, Orally disintegratingOral	Unichem Pharmaceuticals (USA), Inc.	29300-269	29300-0269-2129300-0269-8129300-0269-91
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Unichem Pharmaceuticals (USA), Inc.	29300-316	29300-0316-2129300-0316-81

All 57 Rizatriptan Benzoate NDCs

Other NDCs under ANDA 202490

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 202490
Product	Strength	Form · route	Labeler	Product NDC
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	A-S Medication Solutions	50090-3367
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Golden State Medical Supply, Inc.	51407-681
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	Golden State Medical Supply, Inc.	51407-682
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Rising Pharma Holdings, Inc.	57237-087
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	Rising Pharma Holdings, Inc.	57237-088
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	DIRECT RX	61919-656
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	Proficient Rx LP	71205-644
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Bryant Ranch Prepack	71335-1149
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	Bryant Ranch Prepack	71335-1912
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Bryant Ranch Prepack	71335-2536
Rizatriptan Benzoate	Rizatriptan benzoate 5 mg/1	TabletOral	Direct_Rx	72189-512
Rizatriptan Benzoate	Rizatriptan benzoate 10 mg/1	TabletOral	Proficient Rx LP	82804-202