What is NDC 72189-652?

72189-652 is the product NDC for Metoprolol Succinate ER, Metoprolol succinate 25 mg/1 tablet, film coated, extended release, listed with the FDA by DIrect_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.

DIrect_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Metoprolol Succinate ER?

2 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Metoprolol Succinate ER NDC 72189-652

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-652Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0652Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-652-90	7218906529072189065290	90 TABLET, FILM COATED, EXTENDED RELEASE in 1 BOTTLE (72189-652-90)Marketed from Dec 8, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Metoprolol Succinate ER
Generic name (nonproprietary): metoprolol succinate er
Active ingredients: Metoprolol succinate — 25 mg/1
Dosage form: Tablet, Film coated, Extended release
Route: Oral
Labeler: DIrect_RxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 216916
Marketing start: Dec 8, 2025
Listing expires: Dec 31, 2026
Other FDA classes: Adrenergic beta-Antagonists (Mechanism)
Identifiers: Product ID 72189-652_45723206-1a9e-5299-e063-6294a90ad969SPL ID 45723206-1a9e-5299-e063-6294a90ad969SPL set ID 45723206-1a9d-5299-e063-6294a90ad969RxCUI 866427UNII TH25PD4CCB
Pharmacologic class: beta-Adrenergic Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189065290 followed by a unit qualifier and the quantity

Package 72189-0652-90. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Dec 8, 2025.

Indications (excerpt from the label)

1.1 Hypertension Metoprolol succinate extended-release tablets are indicated for the treatment of hypertension, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including metoprolol. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to ac…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-652

What is NDC 72189-652?: 72189-652 is the product NDC for Metoprolol Succinate ER, Metoprolol succinate 25 mg/1 tablet, film coated, extended release, listed with the FDA by DIrect_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Metoprolol Succinate ER.
What is the active ingredient?: Metoprolol succinate.
Who is the labeler?: DIrect_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Metoprolol Succinate ER?: 2 other product NDCs are listed under this name. See all Metoprolol Succinate ER NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Metoprolol Succinate ER NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Metoprolol Succinate ER	Metoprolol succinate 50 mg/1	Tablet, Extended releaseOral	Direct_Rx	72189-547	72189-0547-90
Metoprolol Succinate ERmetoprolol succinate	Metoprolol succinate 25 mg/1	Tablet, Extended releaseOral	Direct_Rx	61919-754	61919-0754-3061919-0754-90

Other NDCs under ANDA 216916

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 216916
Product	Strength	Form · route	Labeler	Product NDC
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	A-S Medication Solutions	50090-7590
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	A-S Medication Solutions	50090-7591
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	Redpharm Drug	67296-2125
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	NuCare Pharmaceuticals,Inc.	68071-3963
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	Preferred Pharmaceuticals Inc.	68788-4022
Metoprolol Succinate	Metoprolol succinate 50 mg/1	Tablet, Film coated, Extended releaseOral	Preferred Pharmaceuticals Inc.	68788-8869
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	Granules Pharmaceuticals Inc.	70010-780
Metoprolol Succinate	Metoprolol succinate 50 mg/1	Tablet, Film coated, Extended releaseOral	Granules Pharmaceuticals Inc.	70010-781
Metoprolol Succinate	Metoprolol succinate 100 mg/1	Tablet, Film coated, Extended releaseOral	Granules Pharmaceuticals Inc.	70010-782
Metoprolol Succinate	Metoprolol succinate 200 mg/1	Tablet, Film coated, Extended releaseOral	Granules Pharmaceuticals Inc.	70010-783
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	REMEDYREPACK INC.	70518-4531
Metoprolol Succinate	Metoprolol succinate 100 mg/1	Tablet, Film coated, Extended releaseOral	REMEDYREPACK INC.	70518-4533
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	Bryant Ranch Prepack	71335-2592
Metoprolol Succinate	Metoprolol succinate 200 mg/1	Tablet, Film coated, Extended releaseOral	Bryant Ranch Prepack	71335-2811
Metoprolol Succinate	Metoprolol succinate 100 mg/1	Tablet, Film coated, Extended releaseOral	Bryant Ranch Prepack	71335-2945
Metoprolol Succinate	Metoprolol succinate 50 mg/1	Tablet, Film coated, Extended releaseOral	Bryant Ranch Prepack	71335-3052
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	PD-Rx Pharmaceuticals, Inc.	72789-576
Metoprolol Succinate	Metoprolol succinate 25 mg/1	Tablet, Film coated, Extended releaseOral	Proficient Rx LP	82804-262
Metoprolol Succinate	Metoprolol succinate 100 mg/1	Tablet, Film coated, Extended releaseOral	Proficient Rx LP	82804-279
Metoprolol Succinate	Metoprolol succinate 50 mg/1	Tablet, Film coated, Extended releaseOral	Proficient Rx LP	82804-301

Showing 20 of 23.