What is NDC 72189-659?

72189-659 is the product NDC for Metoprolol Tartrate, Metoprolol tartrate 100 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.

Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Metoprolol Tartrate?

224 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Metoprolol Tartrate NDC 72189-659 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-659Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0659Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-659-90	7218906599072189065990	90 TABLET in 1 BOTTLE (72189-659-90)Marketed from Jan 30, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Metoprolol Tartrate
Generic name (nonproprietary): metoprolol tartrate
Active ingredients: Metoprolol tartrate — 100 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Direct_RxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 200981
Marketing start: Jan 30, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic beta-Antagonists (Mechanism)
Identifiers: Product ID 72189-659_499ce022-12a8-e4e5-e063-6394a90a435aSPL ID 499ce022-12a8-e4e5-e063-6394a90a435aSPL set ID 499ce022-12a7-e4e5-e063-6394a90a435aRxCUI 866511UNII W5S57Y3A5L
Pharmacologic class: beta-Adrenergic Blocker

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189065990 followed by a unit qualifier and the quantity

Package 72189-0659-90. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jan 30, 2026.

Indications (excerpt from the label)

1.1 Hypertension Metoprolol tartrate is indicated for the treatment of hypertension in adult patients, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including metoprolol. Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blo…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-659

What is NDC 72189-659?: 72189-659 is the product NDC for Metoprolol Tartrate, Metoprolol tartrate 100 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Metoprolol Tartrate.
What is the active ingredient?: Metoprolol tartrate.
Who is the labeler?: Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Metoprolol Tartrate?: 224 other product NDCs are listed under this name. See all Metoprolol Tartrate NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Metoprolol Tartrate NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Metoprolol Tartratemetoprolol	Metoprolol tartrate 50 mg/1	TabletOral	St. Mary's Medical Park Pharmacy	60760-944	60760-0944-60
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	TabletOral	REMEDYREPACK INC.	70518-4748	70518-4748-00
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	TabletOral	REMEDYREPACK INC.	70518-4714	70518-4714-00
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	Tablet, Film coatedOral	Cardinal Health 107, LLC	55154-0278	55154-0278-00
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	Tablet, Film coatedOral	Cardinal Health 107, LLC	55154-0279	55154-0279-00
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	Direct_Rx	72189-677	72189-0677-90
Metoprolol Tartratemetoprolol	Metoprolol tartrate 100 mg/1	TabletOral	Coupler LLC	67046-1384	67046-1384-03
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	TabletOral	ST. MARY'S MEDICAL PARK PHARMACY	60760-928	60760-0928-90
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	PD-Rx Pharmaceuticals, Inc.	72789-555	72789-0555-90
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	Tablet, Film coatedOral	Safecor Health, LLC	48433-073	48433-0073-20

All 225 Metoprolol Tartrate NDCs

Other NDCs under ANDA 200981

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 200981
Product	Strength	Form · route	Labeler	Product NDC
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	A-S Medication Solutions	50090-7969
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	A-S Medication Solutions	50090-7970
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	Tablet, Film coatedOral	RedPharm Drug, Inc	67296-1903
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	Tablet, Film coatedOral	St. Mary's Medical Park Pharmacy	60760-566
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	Tablet, Film coatedOral	RedPharm Drug, Inc	67296-1903
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	Tablet, Film coatedOral	Direct_Rx	72189-544
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	53401-011
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	53401-015
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	Tablet, Film coatedOral	Bryant Ranch Prepack	71335-0743
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	53401-012
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	Tablet, Film coatedOral	A-S Medication Solutions	50090-6763
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	Tablet, Film coatedOral	A-S Medication Solutions	50090-6764
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	53401-016
Metoprolol Tartrate	Metoprolol tartrate 100 mg/1	TabletOral	Aphena Pharma Solutions - Tennessee, LLC	53401-017
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	TabletOral	Bryant Ranch Prepack	71335-2789
Metoprolol Tartrate	Metoprolol tartrate 37.5 mg/1	Tablet, Film coatedOral	Advagen Pharma Limited	72888-101
Metoprolol Tartrate	Metoprolol tartrate 50 mg/1	TabletOral	ASCLEMED USA INC.	87063-186
Metoprolol Tartrate	Metoprolol tartrate 25 mg/1	TabletOral	ASCLEMED USA INC.	87063-184
Metoprolol Tartrate	Metoprolol tartrate 37.5 mg/1	TabletOral	ASCLEMED USA INC.	87063-185
Metoprolol Tartrate	Metoprolol tartrate 75 mg/1	TabletOral	ASCLEMED USA INC.	87063-187

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