What is NDC 72189-667?

72189-667 is the product NDC for Ibuprofen Famotidine, Ibuprofen 800 mg/1; Famotidine 26.6 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.

Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Ibuprofen Famotidine?

1 other product NDC are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Ibuprofen Famotidine NDC 72189-667

NDC codes

FDA NDC Directory

Product NDC (as listed)72189-667Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72189-0667Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72189-667-90	7218906679072189066790	90 TABLET in 1 BOTTLE (72189-667-90)Marketed from Jun 22, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Ibuprofen Famotidine
Generic name (nonproprietary): ibuprofen famotidine
Active ingredients: Ibuprofen — 800 mg/1Famotidine — 26.6 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Direct_RxNDC labeler code 72189
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 218684
Marketing start: Jun 22, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)Histamine H2 Receptor Antagonists (Mechanism)
Identifiers: Product ID 72189-667_54d9e1fc-507e-1859-e063-6394a90a8c6bSPL ID 54d9e1fc-507e-1859-e063-6394a90a8c6bSPL set ID 54d9e1fc-507d-1859-e063-6394a90a8c6bRxCUI 1100066UNII WK2XYI10QM, 5QZO15J2Z8
Pharmacologic class: Histamine-2 Receptor Antagonist; Nonsteroidal Anti-inflammatory Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472189066790 followed by a unit qualifier and the quantity

Package 72189-0667-90. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 22, 2026. This label includes a boxed warning.

Indications (excerpt from the label)

Ibuprofen and famotidine tablets, a combination of the NSAID ibuprofen and the histamine H2-receptor antagonist famotidine, is indicated for the relief of signs and symptoms of rheumatoid arthritis and osteoarthritis and to decrease the risk of developing upper gastrointestinal ulcers, which in the clinical trials was defined as a gastric and/or duodenal ulcer, in patients who are taking ibuprofen for those indications. The clinical trials primarily enrolled patients less than 65 years of age without a prior history of gastrointestinal ulcer. Controlled trials do not extend beyond 6 months [see Clinical Studies (14), Use in Specific Populations (8.5)].

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72189-667

What is NDC 72189-667?: 72189-667 is the product NDC for Ibuprofen Famotidine, Ibuprofen 800 mg/1; Famotidine 26.6 mg/1 tablet, listed with the FDA by Direct_Rx. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Ibuprofen Famotidine.
What is the active ingredient?: Ibuprofen, Famotidine.
Who is the labeler?: Direct_Rx, NDC labeler code 72189. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Ibuprofen Famotidine?: 1 other product NDC are listed under this name. See all Ibuprofen Famotidine NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Ibuprofen Famotidine NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Ibuprofen Famotidine	Ibuprofen 800 mg/1; Famotidine 26.6 mg/1	Tablet, Film coatedOral	Direct_Rx	72189-641	72189-0641-90

Other NDCs under ANDA 218684

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 218684
Product	Strength	Form · route	Labeler	Product NDC
Ibuprofen and Famotidine	Ibuprofen 800 mg/1; Famotidine 26.6 mg/1	TabletOral	Zydus Lifesciences Limited	70771-1924
Ibuprofen and Famotidine	Ibuprofen 800 mg/1; Famotidine 26.6 mg/1	TabletOral	Viona Pharmaceuticals Inc	72578-214
Ibuprofen and Famotidine	Ibuprofen 800 mg/1; Famotidine 26.6 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0587