NDC codes

FDA NDC Directory
Product NDC (as listed)72288-286Labeler and product segments. Claims need a package NDC.
Product NDC at billing width72288-0286Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
72288-286-2772288028627722880286271 BOTTLE in 1 CARTON (72288-286-27) / 80 TABLET, FILM COATED in 1 BOTTLE (72288-286-00)Marketed from Sep 11, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
migraine relief
Generic name (nonproprietary)
acetaminophen, aspirin, caffeine
Active ingredients
Acetaminophen — 250 mg/1Aspirin — 250 mg/1Caffeine — 65 mg/1
Dosage form
Tablet, Film coated
Route
Oral
Labeler
Amazon.com Services LLCNDC labeler code 72288
Product type
Over-the-counter drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 075794
Marketing start
Listing expires
Other FDA classes
Non-Steroidal (Chemical structure)Central Nervous System Stimulation (Physiologic effect)Cyclooxygenase Inhibitors (Mechanism)Decreased Platelet Aggregation (Physiologic effect)Decreased Prostaglandin Production (Physiologic effect)Xanthines (Chemical structure)
Identifiers
Product ID 72288-286_26495ff4-57bc-4e28-b04c-d2da16be4c27SPL ID 26495ff4-57bc-4e28-b04c-d2da16be4c27
Pharmacologic class
Central Nervous System Stimulant; Methylxanthine; Nonsteroidal Anti-inflammatory Drug; Platelet Aggregation Inhibitor

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472288028627 followed by a unit qualifier and the quantity

Package 72288-0286-27. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 72288-286

What is NDC 72288-286?
72288-286 is the product NDC for migraine relief, Acetaminophen 250 mg/1 + 2 more ingredients tablet, film coated, listed with the FDA by Amazon.com Services LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
migraine relief (Acetaminophen, aspirin, caffeine).
What is the active ingredient?
Acetaminophen, Aspirin, Caffeine.
Who is the labeler?
Amazon.com Services LLC, NDC labeler code 72288. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for migraine relief?
15 other product NDCs are listed under this name. See all migraine relief NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other migraine relief NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
Migraine Reliefacetaminophen, aspirin and caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralCHAIN DRUG MARKETING ASSOCIATION, INC.83324-09983324-0099-24
Migraine Reliefacetaminophen, aspirin and caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralDISCOUNT DRUG MART53943-30553943-0305-03
Migraine Reliefacetaminophen, aspirin and caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralHARRIS TEETER72036-30572036-0305-03
Migraine Reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralFamily Dollar (FAMILY WELLNESS)55319-97055319-0970-1055319-0970-24
Migraine Reliefacetaminophen, aspirin and caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralAAA PHARMACEUTICAL, INC.57344-20557344-0205-01
Migraine Reliefturmeric, curcuma aromatica root, indian frankincense, ginger, feverfewTurmeric 2 [hp_X]/6g + 4 more ingredientsPowderOralRida LLC83004-00383004-0003-01
Migraine Reliefacetaminophen, aspirin and caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTabletOralFSA STORE INC.81522-20581522-0205-03
migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralWalgreen Company0363-123500363-1235-2700363-1235-60
migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralKroger Company30142-89630142-0896-6230142-0896-78
Migraine ReliefibuprofenIbuprofen 200 mg/1Capsule, Liquid filledOralBionpharma Inc.69452-26369452-0263-1169452-0263-7869452-0263-79

All 16 migraine relief NDCs

Other NDCs under ANDA 075794

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 075794
ProductStrengthForm · routeLabelerProduct NDC
basic care migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralAmazon.com Services LLC72288-295
basic care migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralAmazon.com Services LLC72288-374
Care One migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralAmerican Sales Company41520-374
DG Health migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralDolgencorp, LLC55910-374
dg health migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralDolgencorp Inc55910-448
Equaline migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralUnited Natural Foods, Inc. dba UNFI41163-374
foster and thrive migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralStrategic Sourcing Services LLC70677-1133
good neighbor pharmacy migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralAmerisource Bergen24385-365
good sense migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralL. Perrigo Company0113-0374
good sense migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralL. Perrigo Company0113-1619
good sense migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralProficient Rx LP82804-002
good sense migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralSportpharm LLC85766-180
Leader Migraine Reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralCardinal Health 110, LLC. dba Leader70000-0247
leader migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralCardinal Health 110, LLC. dba Leader70000-0611
migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralH E B37808-374
migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralMeijer Distribution Inc41250-374
migraine formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralHyVee Inc42507-374
Migraine Formulaacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralMeijer, Inc.79481-0211
migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralWalgreen Company0363-0374
migraine reliefacetaminophen, aspirin, caffeineAcetaminophen 250 mg/1 + 2 more ingredientsTablet, Film coatedOralWalgreen Company0363-1235

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