What is NDC 72288-312?

72288-312 is the product NDC for Naproxen Sodium, Naproxen sodium 220 mg/1 capsule, liquid filled, listed with the FDA by Amazon.com Services LLC. It has 1 package NDC, shown above in 10- and 11-digit form.

Amazon.com Services LLC, NDC labeler code 72288. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Naproxen Sodium?

144 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Naproxen Sodium NDC 72288-312 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72288-312Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72288-0312Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72288-312-25	7228803122572288031225	180 CAPSULE, LIQUID FILLED in 1 BOTTLE, PLASTIC (72288-312-25)Marketed from Feb 12, 2024

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Naproxen Sodium
Generic name (nonproprietary): naproxen sodium
Active ingredients: Naproxen sodium — 220 mg/1
Dosage form: Capsule, Liquid filled
Route: Oral
Labeler: Amazon.com Services LLCNDC labeler code 72288
Product type: Over-the-counter drug
Marketing category: NDA — New Drug ApplicationApplication NDA 021920
Marketing start: Feb 12, 2024
Listing expires: Dec 31, 2027
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)
Identifiers: Product ID 72288-312_5075f7bb-8b66-de7b-e063-6394a90a4d24SPL ID 5075f7bb-8b66-de7b-e063-6394a90a4d24SPL set ID 04a298dc-c525-8198-e063-6294a90a6f96RxCUI 1112231UNII 9TN87S3A3C
Pharmacologic class: Nonsteroidal Anti-inflammatory Drug

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472288031225 followed by a unit qualifier and the quantity

Package 72288-0312-25. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 27, 2026.

Indications (excerpt from the label)

Uses temporarily relieves minor aches and pains due to: minor pain of arthritis muscular aches backache menstrual cramps headache toothache the common cold temporarily reduces fever

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72288-312

What is NDC 72288-312?: 72288-312 is the product NDC for Naproxen Sodium, Naproxen sodium 220 mg/1 capsule, liquid filled, listed with the FDA by Amazon.com Services LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Naproxen Sodium.
What is the active ingredient?: Naproxen sodium.
Who is the labeler?: Amazon.com Services LLC, NDC labeler code 72288. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Naproxen Sodium?: 144 other product NDCs are listed under this name. See all Naproxen Sodium NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Naproxen Sodium NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
naproxen sodium	Naproxen sodium 220 mg/1	Tablet, Film coatedOral	Amazon.com Services LLC	72288-988	72288-0988-75
Naproxen Sodium	Naproxen sodium 220 mg/1	Tablet, CoatedOral	AAA Pharmaceutical, Inc.	57344-244	57344-0244-03
Naproxen Sodium	Naproxen sodium 550 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0574	80425-0574-0180425-0574-0280425-0574-03
Naproxen Sodium	Naproxen sodium 220 mg/1	Tablet, CoatedOral	HYVEE INC	42507-245	42507-0245-0142507-0245-0842507-0245-14
Naproxen Sodium	Naproxen sodium 220 mg/1	Tablet, CoatedOral	HYVEE INC	42507-844	42507-0844-0142507-0844-14
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	TARGET Corporation	11673-651	11673-0651-78
Naproxen Sodium	Naproxen sodium 220 mg/1	Tablet, Film coatedOral	Safeway	21130-593	21130-0593-79
Naproxen Sodium	Naproxen sodium 550 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0531	80425-0531-0180425-0531-0280425-0531-03
Naproxen Sodium	Naproxen sodium 550 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0532	80425-0532-0180425-0532-0280425-0532-03
Naproxen Sodium	Naproxen sodium 220 mg/1	Tablet, CoatedOral	CHAIN DRUG MARKETING ASSOCIATION, INC.	83324-108	83324-0108-0183324-0108-2483324-0108-50

All 145 Naproxen Sodium NDCs

Other NDCs under NDA 021920

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 021920
Product	Strength	Form · route	Labeler	Product NDC
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Wal-Mart Stores, Inc.	49035-382
naproxen sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Bionpharma Inc.	69452-259
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	DISCOUNT DRUG MART, INC.	53943-179
naproxen sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Bionpharma Inc.	69452-284
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	SUPERVALU INC	41163-079
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	VALU MERCHANDISERS COMPANY	63941-681
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	AMERISOURCE BERGEN	46122-780
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	CHAIN DRUG MARKETING ASSOCIATION INC.	63868-830
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	MEIJER DISTRIBUTION INC	41250-225
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	TARGET Corporation	11673-651
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Premier Value Alliance LLC	68016-056
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	KROGER COMPANY	30142-285
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	HEB	37808-049
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	TOP CARE (Topco Associates LLC)	36800-204
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Rite Aid Corporation	11822-0788
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	WALGREEN COMPANY	0363-0102
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Albertsons Companies	21130-948
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	WALGREEN COMPANY	0363-0177
Alevenaproxen sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Bayer HealthCare LLC.	0280-6080
Naproxen Sodium	Naproxen sodium 220 mg/1	Capsule, Liquid filledOral	Bionpharma Inc.	69452-179

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