Over-the-counter drug · ANDA
loperamide hydrochloride and simethicone (Loperamide hydrochloride, simethicone) NDC 72288-728
Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 · Tablet · Oral · Amazon.com Services LLC
NDC codes
FDA NDC DirectoryProduct NDC (as listed)72288-728Labeler and product segments. Claims need a package NDC.
Product NDC at billing width72288-0728Add the package segment from the table below.
| Package NDC | 11-digit (billing) | Package | Copy |
|---|---|---|---|
| 72288-728-62 | 7228807286272288072862 | 24 BLISTER PACK in 1 CARTON (72288-728-62) / 1 TABLET in 1 BLISTER PACKMarketed from Sep 24, 2026 |
How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules
Product information
- Brand name (proprietary)
- loperamide hydrochloride and simethicone
- Generic name (nonproprietary)
- loperamide hydrochloride, simethicone
- Active ingredients
- Loperamide hydrochloride — 2 mg/1Dimethicone — 125 mg/1
- Dosage form
- Tablet
- Route
- Oral
- Labeler
- Amazon.com Services LLCNDC labeler code 72288
- Product type
- Over-the-counter drug
- Marketing category
- ANDA — Abbreviated New Drug Application (generic)Application ANDA 209837
- Marketing start
- Listing expires
- Other FDA classes
- Opioid Agonists (Mechanism)Skin Barrier Activity (Physiologic effect)
- Identifiers
- Product ID 72288-728_7f28c6e2-df7b-4490-8890-64f980d68dfeSPL ID 7f28c6e2-df7b-4490-8890-64f980d68dfe
- Pharmacologic class
- Opioid Agonist
Billing references
What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.
- HCPCS codeNo match
No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.
- NDC on a medical claim
N472288072862followed by a unit qualifier and the quantityPackage 72288-0728-62. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier
Product label
The FDA listing for this product does not reference a label (SPL) set.
About NDC 72288-728
- What is NDC 72288-728?
- 72288-728 is the product NDC for loperamide hydrochloride and simethicone, Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 tablet, listed with the FDA by Amazon.com Services LLC. It has 1 package NDC, shown above in 10- and 11-digit form.
- What drug is associated with this NDC?
- loperamide hydrochloride and simethicone (Loperamide hydrochloride, simethicone).
- What is the active ingredient?
- Loperamide hydrochloride, Dimethicone.
- Who is the labeler?
- Amazon.com Services LLC, NDC labeler code 72288. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
- What other NDCs exist for loperamide hydrochloride and simethicone?
- 13 other product NDCs are listed under this name. See all loperamide hydrochloride and simethicone NDCs.
- Is there a related HCPCS / J-code?
- Not in Med-Code's curated HCPCS directory. See Billing references above.
Related NDCs: other loperamide hydrochloride and simethicone products
Other finished products listed under the same name: strengths, forms and labelers.
| Product | Strength | Form · route | Labeler | Product NDC | Package NDCs (11-digit) |
|---|---|---|---|---|---|
| Loperamide hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Bionpharma Inc. | 69452-531 | 69452-0531-12 |
| Loperamide Hydrochloride and Simethicone | Dimethicone 125 mg/1; Loperamide hydrochloride 2 mg/1 | TabletOral | IMO-GEN LABS LLC | 84441-713 | 84441-0713-10 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | FSA store INC | 81522-325 | 81522-0325-24 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | WALMART INC. | 79903-223 | 79903-0223-1279903-0223-24 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Family Dollar Stores, LLC | 55319-052 | 55319-0052-75 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Better Living Brands, LLC | 21130-222 | 21130-0222-2421130-0222-76 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Granules India Ltd | 62207-739 | 62207-0739-69 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | WALGREEN CO. | 0363-9606 | 00363-9606-7500363-9606-76 |
| Loperamide hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Bionpharma Inc. | 69452-210 | 69452-0210-0469452-0210-12 |
| Loperamide Hydrochloride and Simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | NORTHEAST PHARMA | 80136-384 | 80136-0384-24 |
Other NDCs under ANDA 209837
Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.
| Product | Strength | Form · route | Labeler | Product NDC |
|---|---|---|---|---|
| anti diarrheal and anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Walgreen Company | 0363-1830 |
| anti diarrheal and anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | CVS Pharmacy | 69842-644 |
| anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Rite Aid Corporation | 11822-1003 |
| Anti Diarrheal Anti Gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Kroger Company | 30142-581 |
| anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | H E B | 37808-714 |
| anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | HyVee Inc | 42507-699 |
| anti diarrheal plus anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Meijer Distribution Inc | 41250-375 |
| Basic Care Loperamide Hydrochloride and Simethiconeloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Amazon.com Services LLC | 72288-001 |
| CareOne Diarrhea and Gas Controlloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | American Sales Company | 41520-772 |
| dg health anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Dolgencorp, LLC | 55910-383 |
| equaline anti diarrheal plus anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | United Natural Foods, Inc. dba UNFI | 41163-553 |
| foster and thrive anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Strategic Sourcing Services LLC | 70677-1105 |
| good neighbor pharmacy anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Amerisource Bergen | 46122-620 |
| good sense anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | L. Perrigo Company | 0113-0087 |
| Good Sense Anti Diarrheal Anti Gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | L. Perrigo Company | 0113-1087 |
| signature care anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Safeway | 21130-183 |
| up and up anti diarrheal anti gasloperamide hydrochloride, simethicone | Loperamide hydrochloride 2 mg/1; Dimethicone 125 mg/1 | TabletOral | Target Corporation | 11673-646 |