What is NDC 72854-001?

72854-001 is the product NDC for Mucinex 12HR Cold and Fever Multi-Symptom, Dextromethorphan hydrobromide 30 mg/1 + 2 more ingredients tablet, extended release, listed with the FDA by Reckitt Benckiser LLC. It has 3 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Mucinex 12HR Cold and Fever Multi-Symptom (Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin).

What is the active ingredient?

Dextromethorphan hydrobromide, Naproxen sodium, Guaifenesin.

Reckitt Benckiser LLC, NDC labeler code 72854. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Mucinex 12HR Cold and Fever Multi-Symptom?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

NDC 72854-001

NDC codes

FDA NDC Directory

Product NDC (as listed)72854-001Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72854-0001Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
72854-001-16	7285400011672854000116	2 BLISTER PACK in 1 CARTON (72854-001-16) / 8 TABLET, EXTENDED RELEASE in 1 BLISTER PACKMarketed from Jun 1, 2026
72854-001-32	7285400013272854000132	4 BLISTER PACK in 1 CARTON (72854-001-32) / 8 TABLET, EXTENDED RELEASE in 1 BLISTER PACKMarketed from Jun 1, 2026
72854-001-50	7285400015072854000150	5 BLISTER PACK in 1 CARTON (72854-001-50) / 10 TABLET, EXTENDED RELEASE in 1 BLISTER PACKMarketed from Jun 1, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Mucinex 12HR Cold and Fever Multi-SymptomSuffix: 12HR Cold and Fever Multi-Symptom
Generic name (nonproprietary): naproxen sodium, dextromethorphan hydrobromide, guaifenesin
Active ingredients: Dextromethorphan hydrobromide — 30 mg/1Naproxen sodium — 110 mg/1Guaifenesin — 600 mg/1
Dosage form: Tablet, Extended release
Route: Oral
Labeler: Reckitt Benckiser LLCNDC labeler code 72854
Product type: Over-the-counter drug
Marketing category: NDA — New Drug ApplicationApplication NDA 217338
Marketing start: Jun 1, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Non-Steroidal (Chemical structure)Cyclooxygenase Inhibitors (Mechanism)Decreased Respiratory Secretion Viscosity (Physiologic effect)Increased Respiratory Secretions (Physiologic effect)Sigma-1 Receptor Agonists (Mechanism)Uncompetitive NMDA Receptor Antagonists (Mechanism)
Identifiers: Product ID 72854-001_53490589-6b93-42b2-e063-6394a90a3c02SPL ID 53490589-6b93-42b2-e063-6394a90a3c02SPL set ID 49f1f415-8017-0974-e063-6294a90a8918RxCUI 2744506UNII 9D2RTI9KYH, 9TN87S3A3C, 495W7451VQ
Pharmacologic class: Expectorant; Nonsteroidal Anti-inflammatory Drug; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472854000116 followed by a unit qualifier and the quantity

Package 72854-0001-16. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Jun 2, 2026.

Indications (excerpt from the label)

Uses ■ helps loosen phlegm (mucus) and thin bronchial secretions to rid the bronchial passageways of bothersome mucus and make coughs more productive ■ temporarily relieves: ■ cough due to minor throat and bronchial irritation as may occur with the common cold or inhaled irritants ■ the intensity of coughing ■ the impulse to cough to help you get to sleep ■ minor aches and pains due to headache and the common cold ■ temporarily reduces fever

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72854-001

What is NDC 72854-001?: 72854-001 is the product NDC for Mucinex 12HR Cold and Fever Multi-Symptom, Dextromethorphan hydrobromide 30 mg/1 + 2 more ingredients tablet, extended release, listed with the FDA by Reckitt Benckiser LLC. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Mucinex 12HR Cold and Fever Multi-Symptom (Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin).
What is the active ingredient?: Dextromethorphan hydrobromide, Naproxen sodium, Guaifenesin.
Who is the labeler?: Reckitt Benckiser LLC, NDC labeler code 72854. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Mucinex 12HR Cold and Fever Multi-Symptom?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Mucinex 12HR Cold and Fever Multi-Symptom NDC 72854-001