NDC codes

FDA NDC Directory
Product NDC (as listed)72888-038Labeler and product segments. Claims need a package NDC.
Product NDC at billing width72888-0038Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
72888-038-0172888003801473 mL in 1 BOTTLE (72888-038-01)Marketed from Jun 23, 2026
72888-038-0272888003802118 mL in 1 BOTTLE (72888-038-02)Marketed from Jun 23, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Promethazine Hydrochloride and Dextromethorphan Hydrobromide
Generic name (nonproprietary)
promethazine hydrochloride and dextromethorphan hydrobromide
Active ingredients
Promethazine hydrochloride — 6.25 mg/5mLDextromethorphan hydrobromide — 15 mg/5mL
Dosage form
Solution
Route
Oral
Product type
Prescription drug
Marketing category
ANDA — Abbreviated New Drug Application (generic)Application ANDA 220869
Marketing start
Listing expires
Other FDA classes
Phenothiazines (Chemical structure)Sigma-1 Receptor Agonists (Mechanism)Uncompetitive NMDA Receptor Antagonists (Mechanism)
Identifiers
Product ID 72888-038_55262a03-3832-160b-e063-6294a90af0d1SPL ID 55262a03-3832-160b-e063-6294a90af0d1SPL set ID 8b60eff2-5759-4bc3-ac16-5ff80aa153a0RxCUI 991528UNII R61ZEH7I1I, 9D2RTI9KYHUPC 0372888038025, 0372888038018
Pharmacologic class
Phenothiazine; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472888003801 followed by a unit qualifier and the quantity

Package 72888-0038-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective . This label includes a boxed warning.

Indications (excerpt from the label)

INDICATIONS AND USAGE Promethazine Hydrochloride and Dextromethorphan Hydrobromide Oral Solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

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