What is NDC 72888-040?

72888-040 is the product NDC for Spironolactone and hydrochlorothiazide, Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1 tablet, listed with the FDA by Advagen Pharma Ltd.. It has 3 package NDCs, shown above in 10- and 11-digit form.

What is the active ingredient?

Spironolactone, Hydrochlorothiazide.

Advagen Pharma Ltd., NDC labeler code 72888. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Spironolactone and hydrochlorothiazide?

11 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Spironolactone and hydrochlorothiazide NDC 72888-040

NDC codes

FDA NDC Directory

Product NDC (as listed)72888-040Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72888-0040Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
72888-040-01	7288800400172888004001	30 TABLET in 1 BOTTLE (72888-040-01)Marketed from Sep 10, 2026
72888-040-02	7288800400272888004002	100 TABLET in 1 BOTTLE (72888-040-02)Marketed from Sep 10, 2026
72888-040-03	7288800400372888004003	1000 TABLET in 1 BOTTLE (72888-040-03)Marketed from Sep 10, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Spironolactone and hydrochlorothiazide
Generic name (nonproprietary): spironolactone and hydrochlorothiazide
Active ingredients: Spironolactone — 25 mg/1Hydrochlorothiazide — 25 mg/1
Dosage form: Tablet
Route: Oral
Labeler: Advagen Pharma Ltd.NDC labeler code 72888
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 220884
Marketing start: Sep 10, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Aldosterone Antagonists (Mechanism)Increased Diuresis (Physiologic effect)Thiazides (Chemical structure)
Identifiers: Product ID 72888-040_5b333a2a-14ce-8106-e063-6394a90aff6cSPL ID 5b333a2a-14ce-8106-e063-6394a90aff6c
Pharmacologic class: Aldosterone Antagonist; Thiazide Diuretic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472888004001 followed by a unit qualifier and the quantity

Package 72888-0040-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 72888-040

What is NDC 72888-040?: 72888-040 is the product NDC for Spironolactone and hydrochlorothiazide, Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1 tablet, listed with the FDA by Advagen Pharma Ltd.. It has 3 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Spironolactone and hydrochlorothiazide.
What is the active ingredient?: Spironolactone, Hydrochlorothiazide.
Who is the labeler?: Advagen Pharma Ltd., NDC labeler code 72888. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Spironolactone and hydrochlorothiazide?: 11 other product NDCs are listed under this name. See all Spironolactone and hydrochlorothiazide NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Spironolactone and hydrochlorothiazide NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Safecor Health LLC	48433-090	48433-0090-20
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	Tablet, Film coatedOral	Prasco Laboratories	66993-188	66993-0188-02
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Mylan Institutional Inc.	42292-017	42292-0017-20
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Sun Pharmaceutical Industries, Inc.	53489-144	53489-0144-0153489-0144-0553489-0144-10
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	63629-1068	63629-1068-01
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	63629-1069	63629-1069-01
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	63629-1071	63629-1071-0163629-1071-0263629-1071-03
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	71335-2202	71335-2202-01
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	71335-2674	71335-2674-0171335-2674-0271335-2674-03
Spironolactone and Hydrochlorothiazide	Spironolactone 25 mg/1; Hydrochlorothiazide 25 mg/1	TabletOral	Bryant Ranch Prepack	72162-1625	72162-1625-0072162-1625-0172162-1625-03+3 more

All 12 Spironolactone and hydrochlorothiazide NDCs