What is NDC 72888-491?

72888-491 is the product NDC for Hydrochlorothiazide, Hydrochlorothiazide 50 mg/5mL solution, listed with the FDA by Advagen Pharma Ltd. It has 1 package NDC, shown above in 10- and 11-digit form.

Advagen Pharma Ltd, NDC labeler code 72888. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Hydrochlorothiazide?

166 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Hydrochlorothiazide NDC 72888-491 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72888-491Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72888-0491Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72888-491-01	7288804910172888049101	1 BOTTLE in 1 CARTON (72888-491-01) / 473 mL in 1 BOTTLEMarketed from Oct 7, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Hydrochlorothiazide
Generic name (nonproprietary): hydrochlorothiazide
Active ingredients: Hydrochlorothiazide — 50 mg/5mL
Dosage form: Solution
Route: Oral
Labeler: Advagen Pharma LtdNDC labeler code 72888
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 218248
Marketing start: Oct 7, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Increased Diuresis (Physiologic effect)Thiazides (Chemical structure)
Identifiers: Product ID 72888-491_5d541861-228e-17b0-e063-6394a90ab61eSPL ID 5d541861-228e-17b0-e063-6394a90ab61e
Pharmacologic class: Thiazide Diuretic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N472888049101 followed by a unit qualifier and the quantity

Package 72888-0491-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

The FDA listing for this product does not reference a label (SPL) set.

About NDC 72888-491

What is NDC 72888-491?: 72888-491 is the product NDC for Hydrochlorothiazide, Hydrochlorothiazide 50 mg/5mL solution, listed with the FDA by Advagen Pharma Ltd. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Hydrochlorothiazide.
What is the active ingredient?: Hydrochlorothiazide.
Who is the labeler?: Advagen Pharma Ltd, NDC labeler code 72888. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Hydrochlorothiazide?: 166 other product NDCs are listed under this name. See all Hydrochlorothiazide NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Hydrochlorothiazide NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	TabletOral	Teva Pharmaceuticals, Inc.	0480-3444	00480-3444-10
hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	CapsuleOral	Preferred Pharmaceuticals Inc.	68788-4192	68788-4192-0168788-4192-0368788-4192-06+2 more
Hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	TabletOral	REMEDYREPACK INC.	70518-4736	70518-4736-00
Hydrochlorothiazide	Hydrochlorothiazide 25 mg/1	TabletOral	Unit Dose Solutions, Inc.	87441-038	87441-0038-01
Hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	TabletOral	Coupler LLC	67046-1664	67046-1664-03
Hydrochlorothiazide	Hydrochlorothiazide 25 mg/1	TabletOral	American Health Packaging	60687-894	60687-0894-01
Hydrochlorothiazide	Hydrochlorothiazide 50 mg/1	TabletOral	REMEDYREPACK INC.	70518-4525	70518-4525-00
Hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	TabletOral	REMEDYREPACK INC.	70518-4466	70518-4466-0070518-4466-01
Hydrochlorothiazide	Hydrochlorothiazide 25 mg/1	TabletOral	REMEDYREPACK INC.	70518-4359	70518-4359-0070518-4359-0170518-4359-02+2 more
Hydrochlorothiazide	Hydrochlorothiazide 12.5 mg/1	TabletOral	Teva Pharmaceuticals USA, Inc.	0172-3444	00172-3444-6000172-3444-80

All 167 Hydrochlorothiazide NDCs