What is NDC 72893-004?

72893-004 is the product NDC for Khapzory (levoleucovorin), Levoleucovorin disodium 175 mg/3.5mL injection, powder, lyophilized, for solution, listed with the FDA by Acrotech Biopharma Inc. It has 1 package NDC, shown above in 10- and 11-digit form.

Acrotech Biopharma Inc, NDC labeler code 72893. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Khapzory?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Khapzory NDC 72893-004 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)72893-004Labeler and product segments. Claims need a package NDC.

Product NDC at billing width72893-0004Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
72893-004-01	7289300040172893000401	1 VIAL in 1 CARTON (72893-004-01) / 3.5 mL in 1 VIALMarketed from Jan 2, 2019

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Khapzory
Generic name (nonproprietary): levoleucovorin
Active ingredients: Levoleucovorin disodium — 175 mg/3.5mL
Dosage form: Injection, Powder, Lyophilized, For solution
Route: Intravenous
Labeler: Acrotech Biopharma IncNDC labeler code 72893
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 211226
Marketing start: Jan 2, 2019
Listing expires: Dec 31, 2027
Other FDA classes: Folic Acid (Chemical structure)
Identifiers: Product ID 72893-004_4b8997a9-ddf8-4618-966a-291d583f24f7SPL ID 4b8997a9-ddf8-4618-966a-291d583f24f7SPL set ID 344f65ac-9f04-49d7-b7c3-4ba19bd7b429RxCUI 1858561, 2106373UNII 5TXQ76K65T
Pharmacologic class: Folate Analog

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N472893000401 followed by a unit qualifier and the quantity

Package 72893-0004-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 17, 2026.

Indications (excerpt from the label)

KHAPZORY is indicated for: rescue after high-dose methotrexate therapy in adult and pediatric patients with osteosarcoma. diminishing the toxicity associated with overdosage of folic acid antagonists or impaired methotrexate elimination adult and pediatric patients. The treatment of adults with metastatic colorectal cancer in combination with fluorouracil. Limitations of Use KHAPZORY is not indicated for pernicious anemia and megaloblastic anemia secondary to lack the of vitamin B 12 because of the risk of progression of neurologic manifestations despite hematologic remission. KHAPZORY is a folate analog indicated for: Rescue after high-dose methotrexate therapy in adults and pediatric patie…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 72893-004

What is NDC 72893-004?: 72893-004 is the product NDC for Khapzory (levoleucovorin), Levoleucovorin disodium 175 mg/3.5mL injection, powder, lyophilized, for solution, listed with the FDA by Acrotech Biopharma Inc. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Khapzory (Levoleucovorin).
What is the active ingredient?: Levoleucovorin disodium.
Who is the labeler?: Acrotech Biopharma Inc, NDC labeler code 72893. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Khapzory?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Khapzory (Levoleucovorin) NDC 72893-004