NDC codes

FDA NDC Directory
Product NDC (as listed)73090-420Labeler and product segments. Claims need a package NDC.
Product NDC at billing width73090-0420Add the package segment from the table below.
Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC11-digit (billing)PackageCopy
73090-420-01730900420011 VIAL, SINGLE-DOSE in 1 BOX (73090-420-01) / 1 INJECTION, POWDER, FOR SOLUTION in 1 VIAL, SINGLE-DOSEMarketed from Apr 23, 2014

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary)
Sylvant
Generic name (nonproprietary)
siltuximab
Active ingredients
Siltuximab — 100 mg/1
Dosage form
Injection, Powder, For solution
Route
Intravenous
Labeler
Recordati Rare Diseases, Inc.NDC labeler code 73090
Product type
Prescription drug
Marketing category
BLA — Biologics License ApplicationApplication BLA 125496
Marketing start
Listing expires
Other FDA classes
Interleukin-6 Antagonists (Mechanism)
Identifiers
Product ID 73090-420_c32bb83e-f9f4-4a6e-928a-f736138996b6SPL ID c32bb83e-f9f4-4a6e-928a-f736138996b6SPL set ID 8d663642-f52e-49c0-a023-2da083fdfc0bRxCUI 1658132, 1658135, 1658139, 1658141UNII T4H8FMA7IM
Pharmacologic class
Interleukin-6 Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N473090042001 followed by a unit qualifier and the quantity

Package 73090-0420-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective .

Indications (excerpt from the label)

SYLVANT is indicated for the treatment of patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. SYLVANT is an interleukin-6 (IL-6) antagonist indicated for the treatment of patients with multicentric Castleman's disease (MCD) who are human immunodeficiency virus (HIV) negative and human herpesvirus-8 (HHV-8) negative. ( 1 ) Limitations of Use SYLVANT was not studied in patients with MCD who are HIV positive or HHV-8 positive because SYLVANT did not bind to virally produced IL-6 in a nonclinical study. Limitations of Use SYLVANT was not studied in patients with MCD who are HIV positive or HHV-8 positi…

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 73090-420

What is NDC 73090-420?
73090-420 is the product NDC for Sylvant (siltuximab), Siltuximab 100 mg/1 injection, powder, for solution, listed with the FDA by Recordati Rare Diseases, Inc.. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?
Sylvant (Siltuximab).
What is the active ingredient?
Siltuximab.
Who is the labeler?
Recordati Rare Diseases, Inc., NDC labeler code 73090. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Sylvant?
1 other product NDC are listed under this name. See all Sylvant NDCs.
Is there a related HCPCS / J-code?
Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Sylvant NDCs
ProductStrengthForm · routeLabelerProduct NDCPackage NDCs (11-digit)
SylvantsiltuximabSiltuximab 400 mg/1Injection, Powder, For solutionIntravenousRecordati Rare Diseases, Inc.73090-42173090-0421-01

Other NDCs under BLA 125496

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under BLA 125496
ProductStrengthForm · routeLabelerProduct NDC
SylvantsiltuximabSiltuximab 400 mg/1Injection, Powder, For solutionIntravenousRecordati Rare Diseases, Inc.73090-421

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