Actimmune (interferon gamma-1b) NDC 75987-111

NDC codes

FDA NDC Directory

Product NDC (as listed)75987-111Labeler and product segments. Claims need a package NDC.

Product NDC at billing width75987-0111Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
75987-111-11	75987011111	12 VIAL, SINGLE-DOSE in 1 CARTON (75987-111-11) / .5 mL in 1 VIAL, SINGLE-DOSE (75987-111-10)Marketed from Dec 1, 2013

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Actimmune
Generic name (nonproprietary): interferon gamma-1b
Active ingredients: Interferon gamma-1b — 100 ug/.5mL
Dosage form: Injection, Solution
Route: Subcutaneous
Labeler: Horizon Therapeutics USA, Inc.
Product type: Prescription drug
Marketing category: BLA — Biologics License ApplicationApplication BLA 103836
Marketing start: Dec 1, 2013
Listing expires: Dec 31, 2027
Other FDA classes: Interferon-gamma (Chemical structure)
Identifiers: Product ID 75987-111_8d803fd6-c715-4d8b-818b-bd5d537c3d60SPL ID 8d803fd6-c715-4d8b-818b-bd5d537c3d60SPL set ID 5d0b1256-1981-4519-94f4-a4a2f98bd8a3RxCUI 240448, 751970UNII 21K6M2I7AG
Pharmacologic class: Interferon gamma

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

Administration

Drug administration (CPT 96360–96549)

When a clinician administers the drug, the administration is reported separately. Codes in this range cover hydration, therapeutic injections and infusions, and chemotherapy or other complex drug administration. The right code depends on route, duration and drug type, and self-administered drugs are not billed this way.

How CPT relates to drug billing

NDC on a medical claim

N475987011111 followed by a unit qualifier and the quantity

Package 75987-0111-11. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Mar 30, 2026.

Indications (excerpt from the label)

ACTIMMUNE is indicated for reducing the frequency and severity of serious infections associated with Chronic Granulomatous Disease (CGD). ACTIMMUNE is indicated for delaying time to disease progression in patients with severe, malignant osteopetrosis (SMO). ACTIMMUNE is an interferon gamma indicated for: Reducing the frequency and severity of serious infections associated with Chronic Granulomatous Disease (CGD) ( 1 ) Delaying time to disease progression in patients with severe, malignant osteopetrosis (SMO) ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)