Night Time Cold and Flu relief liquid filled softgels NDC 76281-603

NDC codes

FDA NDC Directory

Product NDC (as listed)76281-603Labeler and product segments. Claims need a package NDC.

Product NDC at billing width76281-0603Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
76281-603-03	76281060303	2 BLISTER PACK in 1 CARTON (76281-603-03) / 12 CAPSULE, LIQUID FILLED in 1 BLISTER PACKMarketed from Jan 1, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Night Time Cold and Flu relief liquid filled softgels
Generic name (nonproprietary): acetaminophen,dextromethrophan hbr,doxylamine succinate
Active ingredients: Acetaminophen — 325 mg/1Dextromethorphan hydrobromide — 15 mg/1Doxylamine succinate — 6.25 mg/1
Dosage form: Capsule, Liquid filled
Route: Oral
Labeler: AptaPharma Inc.
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 012
Marketing start: Jan 1, 2026
Listing expires: Dec 31, 2027
Other FDA classes: Histamine Receptor Antagonists (Mechanism)Sigma-1 Receptor Agonists (Mechanism)Uncompetitive NMDA Receptor Antagonists (Mechanism)
Identifiers: Product ID 76281-603_8f4959ca-8471-47a4-bd2d-f22d639396cfSPL ID 8f4959ca-8471-47a4-bd2d-f22d639396cfSPL set ID d61e2186-8b59-45f9-96ec-83430a0fe0cbRxCUI 1094549UNII 362O9ITL9D, 9D2RTI9KYH, V9BI9B5YI2
Pharmacologic class: Antihistamine; Sigma-1 Agonist; Uncompetitive N-methyl-D-aspartate Receptor Antagonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N476281060303 followed by a unit qualifier and the quantity

Package 76281-0603-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 10, 2026.

Indications (excerpt from the label)

Uses Temporarily relieves common cold/flu symptoms:

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under M 012

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 012
Product	Strength	Form · route	Labeler	Product NDC
XL-3 Day Timeacetaminophen, dextromethorphan hbr, phenylephrine hcl	Dextromethorphan hydrobromide 10 mg/15mL + 2 more ingredients	LiquidOral	Rnv LLC	84379-441
Halls Sugar Free Watermelonmenthol	Menthol 2.5 mg/1	LozengeOral	Mondelez Global LLC	12546-351
Xpect Cherry Cough Dropscherry cough drops	Menthol 7 mg/1	LozengeOral	Cintas Corporation	42961-232
Childrens TYLENOL COLD PLUS COUGH PLUS SORE THROATacetaminophen and dextromethorphan hydrobromide	Acetaminophen 160 mg/5mL; Dextromethorphan hydrobromide 5 mg/5mL	SuspensionOral	Kenvue Brands LLC	50580-194
Nighttime Cough DMdextromethorphan hbr, doxylamine succinate	Dextromethorphan hydrobromide 30 mg/20mL; Doxylamine succinate 12.5 mg/20mL	SolutionOral	L.N.K. International, Inc.	50844-043
Diphenhydramine HCl	Diphenhydramine hydrochloride 50 mg/1	Tablet, CoatedOral	CVS Pharmacy, Inc.	51316-221
DayTime and Nighttime Cold/Flu Relief Softgels - Combo Packacetaminophen, dextromethorphan hbr, phenylephrine hcl, doxylamine succinate	—	Kit	ARMY AND AIR FORCE EXCHANGE SERVICE	55301-605
Sleep Aid NightTimediphenhydramine hcl	Diphenhydramine hydrochloride 50 mg/30mL	LiquidOral	Dolgencorp, Inc. (DOLLAR GENERAL & REXALL)	55910-981
Codeine-Guaifenesincodeine phosphate and guaifenesin	Codeine phosphate 10 mg/5mL; Guaifenesin 100 mg/5mL	SolutionOral	Method Pharmaceuticals, LLC	58657-500
Dual Action Glacier Mint Cough Suppressant Oral Anestheticmenthol	Menthol 8.3 mg/1	LozengeOral	Ricola USA Inc.	63667-603
DayQuil Cold and Flu w/VapoCOOL, 4ct (PE-free), BSXacetaminophen, dextromethorphan hydrobromide tablet, coated	Dextromethorphan hydrobromide 10 mg/1; Acetaminophen 325 mg/1	Tablet, CoatedOral	Lil' Drug Store Products, Inc.	66715-6204
Multi Symptom Severe Coldacetaminophen, dextromethorphan hbr, phenylephrine hcl	Acetaminophen 500 mg/1 + 2 more ingredients	Powder, For solutionOral	RARITAN PHARMACEUTICALS INC	68163-547
Vicks DayQuil Cough DM plus Congestiondextromethorphan hydrobromide, guaifenesin and phenylephrine hydrochloride	Dextromethorphan hydrobromide 10 mg/15mL + 2 more ingredients	LiquidOral	The Procter & Gamble Manufacturing Company	69423-922
dimaphen dmbrompheniramine maleate, dextromethorphan hbr, phenylephrine hcl	Brompheniramine maleate 2 mg/10mL + 2 more ingredients	SolutionOral	Preferred Pharmaceuticals Inc.	68788-8134
Nighttime Cold and Fluacetaminophen, dextromethorphan hydrobromide, doxylamine succinate	Acetaminophen 650 mg/30mL + 2 more ingredients	LiquidOral	Harris Teeter, LLC	69256-343
Cold and Flu Dayacetaminophen, dextromethorphan hbr, phenylephrine hcl	Acetaminophen 325 mg/15mL + 2 more ingredients	SolutionOral	Walgreen Company	0363-9912
Multi Symptom Cold and Multi Symptom Nighttime Cold Childrensdextromethorphan hbr, guaifenesin, phenylephrine hci, acetaminophen, diphenhydramine hci, phenylephrine hci	—	Kit	CVS Pharmacy	69842-820
Allergy Relief Diphenhydramine HCl 25mg SoftGeldiphenhydramine hydrochloride	Diphenhydramine hydrochloride 25 mg/1	Capsule, Liquid filledOral	Pioneer Life Sciences, LLC	72090-052
SofSkin Vaporizing Chest Rub and Cough Suppressantcamphor, menthol, eucalyptus oil	Camphor (Natural) 4.8 g/100g + 2 more ingredients	OintmentTopical	Viny Health and Beauty Inc	76436-144
Nighttime Cold and Flu Multi Symptom Reliefacetaminophen, dextromethorphan hbr, doxylamine succinate	Acetaminophen 325 mg/1 + 2 more ingredients	Capsule, Liquid filledOral	Shield Pharmaceuticals Corp	83059-0177

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