What is NDC 80425-0144?

80425-0144 is the product NDC for Tizanidine HCL, Tizanidine hydrochloride 4 mg/1 capsule, listed with the FDA by Advanced Rx Pharmacy of Tennessee, LLC. It has 4 package NDCs, shown above in 10- and 11-digit form.

Advanced Rx Pharmacy of Tennessee, LLC, NDC labeler code 80425. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Tizanidine HCL?

5 other product NDCs are listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Tizanidine HCL NDC 80425-0144 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)80425-0144Labeler and product segments. Claims need a package NDC.

Product NDC at billing width80425-0144Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package
80425-0144-1	8042501440180425014401	30 CAPSULE in 1 BOTTLE (80425-0144-1)Marketed from Mar 29, 2019
80425-0144-2	8042501440280425014402	60 CAPSULE in 1 BOTTLE (80425-0144-2)Marketed from Mar 29, 2019
80425-0144-3	8042501440380425014403	90 CAPSULE in 1 BOTTLE (80425-0144-3)Marketed from Mar 29, 2019
80425-0144-4	8042501440480425014404	120 CAPSULE in 1 BOTTLE (80425-0144-4)Marketed from Nov 17, 2025

How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Tizanidine HCL
Generic name (nonproprietary): tizanidine hcl
Active ingredients: Tizanidine hydrochloride — 4 mg/1
Dosage form: Capsule
Route: Oral
Labeler: Advanced Rx Pharmacy of Tennessee, LLCNDC labeler code 80425
Product type: Prescription drug
Marketing category: ANDA — Abbreviated New Drug Application (generic)Application ANDA 212196
Marketing start: Mar 29, 2019
Listing expires: Dec 31, 2026
Other FDA classes: Adrenergic alpha2-Agonists (Mechanism)
Identifiers: Product ID 80425-0144_43cfb518-01fc-0ea4-e063-6394a90a06d3SPL ID 43cfb518-01fc-0ea4-e063-6394a90a06d3SPL set ID c46c7aa3-69db-82dc-e053-2995a90ac251RxCUI 485485UNII B53E3NMY5C
Pharmacologic class: Central alpha-2 Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Oral products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N480425014401 followed by a unit qualifier and the quantity

Package 80425-0144-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Nov 17, 2025.

Indications (excerpt from the label)

1. Indications and Usage Section 1 INDICATIONS & USAGE Tizanidine hydrochloride is a central alpha-2-adrenergic agonist indicated for the management of spasticity. Because of the short duration of therapeutic effect, treatment with tizanidine hydrochloride should be reserved for those daily activities and times when relief of spasticity is most important [see Dosage and Administration (2.1)].

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 80425-0144

What is NDC 80425-0144?: 80425-0144 is the product NDC for Tizanidine HCL, Tizanidine hydrochloride 4 mg/1 capsule, listed with the FDA by Advanced Rx Pharmacy of Tennessee, LLC. It has 4 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Tizanidine HCL.
What is the active ingredient?: Tizanidine hydrochloride.
Who is the labeler?: Advanced Rx Pharmacy of Tennessee, LLC, NDC labeler code 80425. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Tizanidine HCL?: 5 other product NDCs are listed under this name. See all Tizanidine HCL NDCs.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other finished products listed under the same name: strengths, forms and labelers.

Other Tizanidine HCL NDCs
Product	Strength	Form · route	Labeler	Product NDC	Package NDCs (11-digit)
Tizanidine HCl	Tizanidine hydrochloride 2 mg/1	TabletOral	Advanced Rx Pharmacy of Tennessee, LLC	80425-0425	80425-0425-0180425-0425-0280425-0425-03
Tizanidine HCL	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Advanced Rx of Tennessee, LLC	80425-0090	80425-0090-0180425-0090-0280425-0090-03+1 more
Tizanidine HCL	Tizanidine hydrochloride 4 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0024	80425-0024-0180425-0024-0280425-0024-03+1 more
Tizanidine HCL	Tizanidine hydrochloride 4 mg/1	TabletOral	Advanced Rx of Tennessee, LLC	80425-0022	80425-0022-0180425-0022-02
Tizanidine HCl	Tizanidine hydrochloride 4 mg/1	TabletOral	Advanced Rx Pharmacy of Tennessee, LLC	80425-0023	80425-0023-0180425-0023-0280425-0023-03+1 more

Other NDCs under ANDA 212196

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under ANDA 212196
Product	Strength	Form · route	Labeler	Product NDC
Tizanidine Hydrochloride	Tizanidine hydrochloride 2 mg/1	CapsuleOral	Asclemed USA, Inc.	76420-900
Tizanidine Hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Asclemed USA, Inc.	76420-901
Tizanidine Hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Asclemed USA, Inc.	76420-902
Tizanidne hydrochloride	Tizanidine hydrochloride 2 mg/1	CapsuleOral	Bryant Ranch Prepack	63629-8871
Tizanidne hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Bryant Ranch Prepack	63629-8872
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Bryant Ranch Prepack	63629-8873
Tizanidne hydrochloride	Tizanidine hydrochloride 2 mg/1	CapsuleOral	Ascend Laboratories, LLC	67877-610
Tizanidne hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Ascend Laboratories, LLC	67877-611
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Ascend Laboratories, LLC	67877-612
Tizanidne hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Preferred Pharmaceuticals Inc.	68788-8798
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Bryant Ranch Prepack	71335-2077
Tizanidne hydrochloride	Tizanidine hydrochloride 2 mg/1	CapsuleOral	Bryant Ranch Prepack	71335-2208
Tizanidne hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Bryant Ranch Prepack	71335-2209
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Bryant Ranch Prepack	71335-2210
Tizanidne hydrochloride	Tizanidine hydrochloride 2 mg/1	CapsuleOral	Bryant Ranch Prepack	72162-1860
Tizanidne hydrochloride	Tizanidine hydrochloride 4 mg/1	CapsuleOral	Bryant Ranch Prepack	72162-1861
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Bryant Ranch Prepack	72162-1862
Tizanidne hydrochloride	Tizanidine hydrochloride 6 mg/1	CapsuleOral	Asclemed USA, Inc.	76420-231