What is NDC 81777-105?

81777-105 is the product NDC for Xesso Strawberry Rear Comfort Glide 4% Lidocaine, Lidocaine hydrochloride 4.625 g/100mL gel, listed with the FDA by Premium Natural Cosmetics Inc. It has 1 package NDC, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Xesso Strawberry Rear Comfort Glide 4% Lidocaine (Lidocaine).

Premium Natural Cosmetics Inc, NDC labeler code 81777. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Xesso Strawberry Rear Comfort Glide 4% Lidocaine?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

NDC 81777-105

NDC codes

FDA NDC Directory

Product NDC (as listed)81777-105Labeler and product segments. Claims need a package NDC.

Product NDC at billing width81777-0105Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
81777-105-01	8177701050181777010501	245 mL in 1 BOTTLE, PLASTIC (81777-105-01)Marketed from Dec 13, 2022

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Xesso Strawberry Rear Comfort Glide 4% Lidocaine
Generic name (nonproprietary): lidocaine
Active ingredients: Lidocaine hydrochloride — 4.625 g/100mL
Dosage form: Gel
Route: Rectal
Labeler: Premium Natural Cosmetics IncNDC labeler code 81777
Product type: Over-the-counter drug
Marketing category: OTC monograph drugApplication M 015
Marketing start: Dec 13, 2022
Listing expires: Dec 31, 2026
Other FDA classes: Amides (Chemical structure)Local Anesthesia (Physiologic effect)
Identifiers: Product ID 81777-105_4162e5d1-8387-b313-e063-6294a90afc0dSPL ID 4162e5d1-8387-b313-e063-6294a90afc0dSPL set ID efba09fc-6dd7-0f73-e053-2995a90a628aUNII V13007Z41A
Pharmacologic class: Amide Local Anesthetic; Antiarrhythmic

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No drug-specific HCPCS code in Med-Code's directory for this product. The directory is curated and not complete — check the current CMS HCPCS file before billing.

NDC on a medical claim

N481777010501 followed by a unit qualifier and the quantity

Package 81777-0105-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Oct 17, 2025.

Indications (excerpt from the label)

Use For temporary relief of pain, soreness, or burning in the perianal area.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 81777-105

What is NDC 81777-105?: 81777-105 is the product NDC for Xesso Strawberry Rear Comfort Glide 4% Lidocaine, Lidocaine hydrochloride 4.625 g/100mL gel, listed with the FDA by Premium Natural Cosmetics Inc. It has 1 package NDC, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Xesso Strawberry Rear Comfort Glide 4% Lidocaine (Lidocaine).
What is the active ingredient?: Lidocaine hydrochloride.
Who is the labeler?: Premium Natural Cosmetics Inc, NDC labeler code 81777. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Xesso Strawberry Rear Comfort Glide 4% Lidocaine?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.

Other NDCs under M 015

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under M 015
Product	Strength	Form · route	Labeler	Product NDC
Pramoxine Hydrochloride Anorectalpramoxine hydrochloride	Pramoxine hydrochloride 1 mg/mL	LotionTopical	Stratus Pharmaceuticals	58980-522
Ma Ying Long Musk Hemorrhoidspetrolatum, zinc oxide	Petrolatum 779.9 mg/g; Zinc oxide 76 mg/g	OintmentTopical	Mayinglong Pharmaceutical Group Co., Ltd.	68511-997
Mayinglong Hemorrhoidalpetrolatum, zinc oxide	Petrolatum 779.9 mg/g; Zinc oxide 76 mg/g	OintmentTopical	Mayinglong Pharmaceutical Group Co., Ltd.	68511-998
hemorrhoidal maximum strength pain reliefglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Kroger Company	30142-944
Preparation Hcocoa butter, phenylephrine hydrochloride, and witch hazel	—	Kit	Haleon US Holdings LLC	0573-2884
Hemorrhoidalmineral oil, petrolatum, phenylephrine hcl	Mineral oil 14 g/100g + 2 more ingredients	OintmentRectal	Kroger Company	30142-188
rexall hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Dolgencorp Inc	55910-279
Witch Hazel	Witch hazel 860 mg/mL	LiquidTopical	CVS Pharmacy, Inc.	59779-045
Dermatool Hemorrhoidalglycerin, lidocaine, petrolatum, phenylephrine hcl	Lidocaine 5 g/100g + 3 more ingredients	CreamTopical	Papalo Group LLC	84728-413
Acolye Numbing Cream Anorectal(Hemorrhoidal) Creamlidocaine	Lidocaine 5 g/100g	CreamTopical	Guangzhou Haishi Biological Technology Co., Ltd.	60771-0028
Hemorrhoid Anestheticmineral oil, petrolatum, phenylephrine hcl	Petrolatum .749 g/g + 2 more ingredients	OintmentTopical	Savvy Care and Cosmetics	83650-110
hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	Meijer Distribution Inc	41250-279
Lidocaine Numbing Creamlidocaine	Lidocaine .05 g/g	CreamTopical	Shanghai Chuangshi Medical Technology (Group) Co., Ltd.	73557-311
RWWXII Deep Numbing Cream(Anorectal Hemorrhoidal Cream)lidocaine	Lidocaine 5 g/100g	CreamTopical	Guangzhou Haishi Biological Technology Co., Ltd.	60771-0027
Barrier Protectant Creambarrier cream	Menthol 1 mg/g; Zinc oxide 200 mg/g	OintmentTopical	Cardinal Health	63517-003
ER Hemorrhoidphenylephrine hcl	Mineral oil .14 g/g + 2 more ingredients	CreamRectal	EVER READY FIRST AID	72976-018
ANIXIKE Numbinglidocaine4% numbing	Lidocaine 4 g/100g	CreamTopical	Jiangxi Yudexi Pharmaceutical Co., LTD	85248-166
Meijer Maximum strength pain relieving cleansingbenzalkonium chloride and lidocaine hydrochloride	Benzalkonium chloride .13 g/100mL; Lidocaine hydrochloride 4 g/100mL	LiquidTopical	MEIJER DISTRIBUTION, INC.	41250-287
hemorrhoidalglycerin, phenylephrine hcl, pramoxine hcl, white petrolatum	Glycerin 14.4 g/100g + 3 more ingredients	CreamTopical	Meijer Distribution Inc	41250-944
Equaline Hemorrhoidalcocoa butter, phenylephrine hcl	Cocoa butter 2211 mg/1; Phenylephrine hydrochloride 6.5 mg/1	SuppositoryRectal	United Natural Foods, Inc. dba UNFI	41163-279

Showing 20 of 40.

Xesso Strawberry Rear Comfort Glide 4% Lidocaine (Lidocaine) NDC 81777-105