Over-the-counter drug · UNAPPROVED DRUG OTHER
BiEST 5.0 Estrogen Cream NDC 82018-0009
estriol,estradiol · Estriol 4 mg/85g; Estradiol 1 mg/85g · Cream · Transdermal · SHYNE BRANDS
NDC codes
FDA NDC Directory| Package NDC | 11-digit (billing) | Package | Copy |
|---|---|---|---|
| 82018-0009-3 | 82018000903 | 85 g in 1 BOTTLE, PUMP (82018-0009-3)Marketed from Jun 1, 2025 |
How the 11-digit form is made: The package segment has 1 digit, so one leading zero is added to it (5-4-1 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules
Product information
- Brand name (proprietary)
- BiEST 5.0 Estrogen Cream
- Generic name (nonproprietary)
- estriol,estradiol
- Active ingredients
- Estriol — 4 mg/85gEstradiol — 1 mg/85g
- Dosage form
- Cream
- Route
- Transdermal
- Labeler
- SHYNE BRANDS
- Product type
- Over-the-counter drug
- Marketing category
- Unapproved drug (other)
- Marketing start
- Listing expires
- Other FDA classes
- Estradiol Congeners (Chemical structure)Estrogen Receptor Agonists (Mechanism)
- Identifiers
- Product ID 82018-0009_37ca001c-de9a-f819-e063-6294a90a4c08SPL ID 37ca001c-de9a-f819-e063-6294a90a4c08SPL set ID c4d3860f-c211-b18c-e053-2a95a90a4474UNII FB33469R8E, 4TI98Z838EUPC 0852178008346
- Pharmacologic class
- Estrogen
Billing references
What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.
- HCPCS codeNo match
No HCPCS code in Med-Code's directory. Transdermal products like this are usually dispensed by a pharmacy and billed by NDC.
- NDC on a medical claim
N482018000903followed by a unit qualifier and the quantityPackage 82018-0009-03. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier
Product label
Current FDA label (SPL), effective .
Indications (excerpt from the label)
USES: This is a topical cream that contains bio-identical estriol and estradiol derived from wild yam and formulated in an 80:20 ratio. When applied to the skin it can help balance your hormones and provide temporary relief from menopausal symptoms such as hot flashes. DIRECTIONS: Apply once or twice a day. Massage into inner arms, thighs, chest or apply to inner forearm and rub arms together or use as directed by your Physician.
Excerpt only. Read the full label for complete information.