neffy (epinephrine) NDC 82580-010

NDC codes

FDA NDC Directory

Product NDC (as listed)82580-010Labeler and product segments. Claims need a package NDC.

Product NDC at billing width82580-0010Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
82580-010-02	82580001002	2 BLISTER PACK in 1 CARTON (82580-010-02) / 1 VIAL, SINGLE-DOSE in 1 BLISTER PACK / 100 uL in 1 VIAL, SINGLE-DOSEMarketed from Mar 5, 2025

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): neffy
Generic name (nonproprietary): epinephrine
Active ingredients: Epinephrine — 1 mg/100uL
Dosage form: Spray
Route: Nasal
Labeler: ARS Pharmaceuticals Operations, Inc.
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 214697
Marketing start: Mar 5, 2025
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha-Agonists (Mechanism)Adrenergic beta-Agonists (Mechanism)Catecholamines (Chemical structure)
Identifiers: Product ID 82580-010_8c27cd52-6215-4cf8-98cc-f8816bf4c690SPL ID 8c27cd52-6215-4cf8-98cc-f8816bf4c690SPL set ID a1758142-a905-401d-8961-05829f51023aRxCUI 2693442, 2693448, 2709207, 2709209UNII YKH834O4BH
Pharmacologic class: Catecholamine; alpha-Adrenergic Agonist; beta-Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Nasal products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N482580001002 followed by a unit qualifier and the quantity

Package 82580-0010-02. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective Apr 9, 2026.

Indications (excerpt from the label)

Neffy is indicated for emergency treatment of type I allergic reactions, including anaphylaxis, in adult and pediatric patients who weigh 15 kg or greater. Neffy is an alpha and beta-adrenergic receptor agonist indicated for emergency treatment of type I allergic reactions, including anaphylaxis, in adult and pediatric patients who weigh 15 kg or greater. ( 1 )

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

Other NDCs under NDA 214697

Products listed under the same FDA application: other strengths and forms, and repackagers who relabel the same product.

FDA NDC Directory listings under NDA 214697
Product	Strength	Form · route	Labeler	Product NDC
neffyepinephrine	Epinephrine 1 mg/100uL	SprayNasal	Sportpharm LLC	85766-129
neffyepinephrine	Epinephrine 2 mg/100uL	SprayNasal	Sportpharm LLC	85766-130
neffyepinephrine	Epinephrine 2 mg/100uL	SprayNasal	Medical Purchasing Solutions, LLC	71872-7330
neffyepinephrine	Epinephrine 2 mg/100uL	SprayNasal	ARS Pharmaceuticals Operations, Inc.	82580-020