What is NDC 82667-200?

82667-200 is the product NDC for Iopidine 1%, Apraclonidine hydrochloride 10 mg/mL solution/ drops, listed with the FDA by Harrow Eye, LLC. It has 2 package NDCs, shown above in 10- and 11-digit form.

What drug is associated with this NDC?

Iopidine 1% (Apraclonidine hydrochloride ophthalmic solution).

Harrow Eye, LLC, NDC labeler code 82667. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.

What other NDCs exist for Iopidine 1%?

None: this is the only finished product listed under this name.

Is there a related HCPCS / J-code?

Not in Med-Code's curated HCPCS directory.

Iopidine 1% NDC 82667-200 | National Drug Code

NDC codes

FDA NDC Directory

Product NDC (as listed)82667-200Labeler and product segments. Claims need a package NDC.

Product NDC at billing width82667-0200Add the package segment from the table below.

Package NDCs as listed with the FDA, and the 11-digit 5-4-2 form used on claims. The highlighted digit is the added leading zero.
Package NDC	11-digit (billing)	Package	Copy
82667-200-01	8266702000182667020001	12 POUCH in 1 CARTON (82667-200-01) / 2 VIAL, SINGLE-DOSE in 1 POUCH / .1 mL in 1 VIAL, SINGLE-DOSEMarketed from Aug 1, 2023
82667-200-05	8266702000582667020005	5 POUCH in 1 CARTON (82667-200-05) / 5 VIAL, SINGLE-DOSE in 1 POUCH / .1 mL in 1 VIAL, SINGLE-DOSEMarketed from May 1, 2026

How the 11-digit form is made: The product segment has 3 digits, so one leading zero is added to it (5-3-2 → 5-4-2). Formatting the NDC does not by itself make it billable — the product, package and quantity must match what was dispensed or administered, and payer rules apply. Conversion rules

Product information

Brand name (proprietary): Iopidine 1%
Generic name (nonproprietary): apraclonidine hydrochloride ophthalmic solution
Active ingredients: Apraclonidine hydrochloride — 10 mg/mL
Dosage form: Solution/ drops
Route: Ophthalmic
Labeler: Harrow Eye, LLCNDC labeler code 82667
Product type: Prescription drug
Marketing category: NDA — New Drug ApplicationApplication NDA 019779
Marketing start: Aug 1, 2023
Listing expires: Dec 31, 2027
Other FDA classes: Adrenergic alpha-Agonists (Mechanism)
Identifiers: Product ID 82667-200_515542b6-cc36-ff77-e063-6294a90ad59eSPL ID 515542b6-cc36-ff77-e063-6294a90ad59eSPL set ID 00f18845-ccde-8678-e063-6294a90a3374RxCUI 211020, 308346UNII D2VW67N38H
Pharmacologic class: alpha-Adrenergic Agonist

Billing references

What Med-Code can say about coding this product, and where each statement comes from. Nothing here is inferred from the name alone.

HCPCS codeNo match

No HCPCS code in Med-Code's directory. Ophthalmic products like this are usually dispensed by a pharmacy and billed by NDC.

NDC on a medical claim

N482667020001 followed by a unit qualifier and the quantity

Package 82667-0200-01. Unit qualifiers: F2 (international unit), GR (gram), ME (milligram), ML (milliliter), UN (unit (each)). The qualifier and quantity depend on what was given. About the N4 qualifier

Product label

Current FDA label (SPL), effective May 8, 2026.

Indications (excerpt from the label)

INDICATIONS AND USAGE IOPIDINE 1% Ophthalmic Solution is indicated to control or prevent post-surgical elevations in IOP that occur in patients after argon laser trabeculoplasty, argon laser iridotomy or Nd:YAG posterior capsulotomy.

Excerpt only. Read the full label for complete information.

Full label on DailyMed (opens in a new tab)

About NDC 82667-200

What is NDC 82667-200?: 82667-200 is the product NDC for Iopidine 1%, Apraclonidine hydrochloride 10 mg/mL solution/ drops, listed with the FDA by Harrow Eye, LLC. It has 2 package NDCs, shown above in 10- and 11-digit form.
What drug is associated with this NDC?: Iopidine 1% (Apraclonidine hydrochloride ophthalmic solution).
What is the active ingredient?: Apraclonidine hydrochloride.
Who is the labeler?: Harrow Eye, LLC, NDC labeler code 82667. The labeler is the company responsible for the label; it may be the manufacturer, a repackager or a distributor.
What other NDCs exist for Iopidine 1%?: None: this is the only finished product listed under this name.
Is there a related HCPCS / J-code?: Not in Med-Code's curated HCPCS directory. See Billing references above.