In short

Alprolix is billed under HCPCS J7201 — Injection, factor ix, fc fusion protein, (recombinant), alprolix, 1 i.u.. One billing unit is 1 IU. CMS's crosswalk lists 6 Alprolix NDCs under this code.

J7201 code details

Reference

J7201
Injection, factor ix, fc fusion protein, (recombinant), alprolix, 1 i.u.Billing unit: 1 IU
Labelers
Bioverativ Therapeutics Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$3.761
Per1 iu
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Alprolix units and claim line

Enter the dose given to get the J7201 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Alprolix NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Alprolix NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
71104-0911-01J7201Bioverativ Therapeutics Inc.11
71104-0922-01J7201Bioverativ Therapeutics Inc.11
71104-0933-01J7201Bioverativ Therapeutics Inc.11
71104-0944-01J7201Bioverativ Therapeutics Inc.11
71104-0966-01J7201Bioverativ Therapeutics Inc.11
71104-0977-01J7201Bioverativ Therapeutics Inc.11

Alprolix: common questions

What is the J-code for Alprolix?
Alprolix is billed under HCPCS J7201 — Injection, factor ix, fc fusion protein, (recombinant), alprolix, 1 i.u.. One billing unit is 1 IU. CMS's crosswalk lists 6 Alprolix NDCs under this code.
How many J7201 billing units are in a package of Alprolix?
CMS lists 1 billing units per package, depending on the NDC, where one unit is 1 IU. Units to report are based on the dose given, not the package.
Is J7201 a CPT code?
No. J7201 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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