In short

Aminocaproic Acid is billed under HCPCS J0281 — Injection, aminocaproic acid, 1 gram. One billing unit is 1 gm. CMS's crosswalk lists 4 Aminocaproic Acid NDCs under this code.

J0281 code details

Reference

J0281
Injection, aminocaproic acid, 1 gramBilling unit: 1 gm
Labelers
American Regent, Inc.; Civica, Inc.; Henry Schein Inc.; Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$1.738
Per1 gm
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Aminocaproic Acid units and claim line

Enter the dose given to get the J0281 units and the NDC line for the CMS-1500 and the 837P.

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Aminocaproic Acid NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Aminocaproic Acid NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9812-20J0281Henry Schein Inc.205
00409-4346-73J0281Pfizer Inc25 × 20125
00517-9191-25J0281American Regent, Inc.25 × 20125
72572-0015-25J0281Civica, Inc.25 × 20125

Aminocaproic Acid: common questions

What is the J-code for Aminocaproic Acid?
Aminocaproic Acid is billed under HCPCS J0281 — Injection, aminocaproic acid, 1 gram. One billing unit is 1 gm. CMS's crosswalk lists 4 Aminocaproic Acid NDCs under this code.
How many J0281 billing units are in a package of Aminocaproic Acid?
CMS lists 5 to 125 billing units per package, depending on the NDC, where one unit is 1 gm. Units to report are based on the dose given, not the package.
Is J0281 a CPT code?
No. J0281 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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