In short

Aminophylline is billed under HCPCS J0280 — Injection, aminophyllin, up to 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 8 Aminophylline NDCs under this code.

J0280 code details

Reference

J0280
Injection, aminophyllin, up to 250 mgBilling unit: 250 mg
Labelers
HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$10.757
Per250 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Aminophylline units and claim line

Enter the dose given to get the J0280 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Aminophylline NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Aminophylline NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9813-10J0280Henry Schein Inc.101
00404-9814-20J0280Henry Schein Inc.202
00409-5921-01J0280Pfizer Inc25 × 1025
00409-5922-01J0280Pfizer Inc25 × 2050
51662-1204-01J0280HF Acquisition Co. LLC, DBA HealthFirst101
51662-1204-03J0280HF Acquisition Co. LLC, DBA HealthFirst25 × 1025
51662-1341-01J0280HF Acquisition Co. LLC, DBA HealthFirst202
51662-1341-03J0280HF Acquisition Co. LLC, DBA HealthFirst25 × 2050

Aminophylline: common questions

What is the J-code for Aminophylline?
Aminophylline is billed under HCPCS J0280 — Injection, aminophyllin, up to 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 8 Aminophylline NDCs under this code.
How many J0280 billing units are in a package of Aminophylline?
CMS lists 1 to 50 billing units per package, depending on the NDC, where one unit is 250 mg. Units to report are based on the dose given, not the package.
Is J0280 a CPT code?
No. J0280 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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