HCPCS drug code · CMS crosswalk
Brixadi (monthly dosing) J-Code / HCPCS Code
In short
Brixadi (monthly dosing) is billed under HCPCS J0578 — Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy. One billing unit is greater than 7 days and up to 28 days of therapy. CMS's crosswalk lists 3 Brixadi (monthly dosing) NDCs under this code.
Reference
- J0578
- Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapyBilling unit: greater than 7 days and up to 28 days of therapy
- Labelers
- Braeburn Inc.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Brixadi (monthly dosing) units and claim line
Enter the dose given to get the J0578 units and the NDC line for the CMS-1500 and the 837P.
Enter the units to build the claim line.
Brixadi (monthly dosing) NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 58284-0228-01 | J0578 | Braeburn Inc. | 0.36 | 1 |
| 58284-0264-01 | J0578 | Braeburn Inc. | 0.18 | 1 |
| 58284-0296-01 | J0578 | Braeburn Inc. | 0.27 | 1 |
Brixadi (monthly dosing): common questions
- What is the J-code for Brixadi (monthly dosing)?
- Brixadi (monthly dosing) is billed under HCPCS J0578 — Injection, buprenorphine extended release (brixadi), greater than 7 days and up to 28 days of therapy. One billing unit is greater than 7 days and up to 28 days of therapy. CMS's crosswalk lists 3 Brixadi (monthly dosing) NDCs under this code.
- How many J0578 billing units are in a package of Brixadi (monthly dosing)?
- CMS lists 1 billing units per package, depending on the NDC, where one unit is greater than 7 days and up to 28 days of therapy. Units to report are based on the dose given, not the package.
- Is J0578 a CPT code?
- No. J0578 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.
Other codes for the same drug
- J0570Buprenorphine implant, 74.2 mg
- J0571Buprenorphine, oral, 1 mg
- J0572Buprenorphine/naloxone, oral, less than or equal to 3 mg buprenorphine
- J0573Buprenorphine/naloxone, oral, greater than 3 mg, but less than or equal to 6 mg buprenorphine
- J0574Buprenorphine/naloxone, oral, greater than 6 mg, but less than or equal to 10 mg buprenorphine
- J0575Buprenorphine/naloxone, oral, greater than 10 mg buprenorphine
- J0577Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy
- J0592Injection, buprenorphine hydrochloride, 0.1 mg
- Q9991Injection, buprenorphine extended-release (sublocade), less than or equal to 100 mg
- Q9992Injection, buprenorphine extended-release (sublocade), greater than 100 mg