In short

Brixadi (weekly dosing) is billed under HCPCS J0577 — Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy. One billing unit is less than or equal to 7 days of therapy. CMS's crosswalk lists 4 Brixadi (weekly dosing) NDCs under this code.

J0577 code details

Reference

J0577
Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapyBilling unit: less than or equal to 7 days of therapy
Labelers
Braeburn Inc.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$433.167
Perless than or equal to 7 days of therapy
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Brixadi (weekly dosing) units and claim line

Enter the dose given to get the J0577 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Brixadi (weekly dosing) NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Brixadi (weekly dosing) NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
58284-0208-01J0577Braeburn Inc.0.161
58284-0216-01J0577Braeburn Inc.0.321
58284-0224-01J0577Braeburn Inc.0.481
58284-0232-01J0577Braeburn Inc.0.641

Brixadi (weekly dosing): common questions

What is the J-code for Brixadi (weekly dosing)?
Brixadi (weekly dosing) is billed under HCPCS J0577 — Injection, buprenorphine extended-release (brixadi), less than or equal to 7 days of therapy. One billing unit is less than or equal to 7 days of therapy. CMS's crosswalk lists 4 Brixadi (weekly dosing) NDCs under this code.
How many J0577 billing units are in a package of Brixadi (weekly dosing)?
CMS lists 1 billing units per package, depending on the NDC, where one unit is less than or equal to 7 days of therapy. Units to report are based on the dose given, not the package.
Is J0577 a CPT code?
No. J0577 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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