How many J0665 billing units are in a package of Bupivacaine HCl?

CMS lists 50 to 12,500 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.

No. J0665 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Bupivacaine HCl J-Code J0665 — Billing Units & NDCs

In short

Bupivacaine HCl is billed under HCPCS J0665 — Injection, bupivicaine, not otherwise specified, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 61 Bupivacaine HCl NDCs under this code.

J0665 code details

Reference

J0665: Injection, bupivicaine, not otherwise specified, 0.5 mgBilling unit: 0.5 mg
Labelers: A-S Medication Solutions; Brookfield Pharmaceuticals, LLC; Eugia US LLC; Fosun Pharma Usa Inc.; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; Hikma Pharmaceuticals USA Inc.; Meitheal Pharmaceuticals Inc.and 4 more

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$0.01

Per0.5 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Bupivacaine HCl units and claim line

Enter the dose given to get the J0665 units and the NDC line for the CMS-1500 and the 837P.

Dose given (mg)

HCPCS units (1 unit = 0.5 mg)

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the dose given to build the claim line.

Bupivacaine HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Bupivacaine HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
00143-9328-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 50	2500
00143-9329-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 50	5000
00143-9330-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 10	500
00143-9331-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 10	1000
00143-9332-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 10	1500
00143-9333-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 30	1500
00143-9334-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 30	3000
00143-9335-10	J0665	Hikma Pharmaceuticals USA Inc.	10 × 30	4500
00404-9826-50	J0665	Henry Schein Inc.	50	250
00404-9827-50	J0665	Henry Schein Inc.	50	500
00409-1159-01	J0665	Pfizer Inc	25 × 10	1250
00409-1159-02	J0665	Pfizer Inc	25 × 30	3750
00409-1159-10	J0665	Pfizer Inc	25 × 30	3750
00409-1160-01	J0665	Pfizer Inc	25 × 50	6250
00409-1162-01	J0665	Pfizer Inc	25 × 10	2500
00409-1162-02	J0665	Pfizer Inc	25 × 30	7500
00409-1163-01	J0665	Pfizer Inc	25 × 50	12500
00409-1165-01	J0665	Pfizer Inc	25 × 10	3750
00409-1165-02	J0665	Pfizer Inc	25 × 30	11250
50090-4516-00	J0665	A-S Medication Solutions	50	500
51662-1396-01	J0665	HF Acquisition Co. LLC, DBA HealthFirst	50	500
51662-1396-03	J0665	HF Acquisition Co. LLC, DBA HealthFirst	25 × 50	12500
51662-1581-03	J0665	HF Acquisition Co. LLC, DBA HealthFirst	25 × 50	6250
52584-0465-57	J0665	Henry Schein Inc.	50	250
52584-0467-57	J0665	Henry Schein Inc.	50	500
55150-0167-10	J0665	Eugia US LLC	25 × 10	1250
55150-0168-30	J0665	Eugia US LLC	25 × 30	3750
55150-0169-10	J0665	Eugia US LLC	25 × 10	2500
55150-0170-30	J0665	Eugia US LLC	25 × 30	7500
55150-0171-10	J0665	Eugia US LLC	25 × 10	3750
55150-0172-30	J0665	Eugia US LLC	25 × 30	11250
55150-0249-50	J0665	Eugia US LLC	25 × 50	6250
55150-0250-50	J0665	Eugia US LLC	25 × 50	12500
70069-0752-25	J0665	Somerset Pharma, LLC	25 × 50	6250
70594-0114-02	J0665	Xellia Pharmaceuticals USA, LLC.	10 × 10	500
70594-0115-01	J0665	Xellia Pharmaceuticals USA, LLC.	30	150
70594-0116-01	J0665	Xellia Pharmaceuticals USA, LLC.	50	250
70594-0117-02	J0665	Xellia Pharmaceuticals USA, LLC.	10 × 10	1000
70594-0118-01	J0665	Xellia Pharmaceuticals USA, LLC.	30	300
70594-0119-01	J0665	Xellia Pharmaceuticals USA, LLC.	50	500
70594-0120-02	J0665	Xellia Pharmaceuticals USA, LLC.	10 × 10	1500
70594-0121-01	J0665	Xellia Pharmaceuticals USA, LLC.	30	450
71288-0721-11	J0665	Meitheal Pharmaceuticals Inc.	10	50
71288-0722-32	J0665	Meitheal Pharmaceuticals Inc.	30	150
71288-0723-52	J0665	Meitheal Pharmaceuticals Inc.	50	250
71288-0724-11	J0665	Meitheal Pharmaceuticals Inc.	10	100
71288-0725-32	J0665	Meitheal Pharmaceuticals Inc.	30	300
71288-0726-52	J0665	Meitheal Pharmaceuticals Inc.	50	500
71288-0727-11	J0665	Meitheal Pharmaceuticals Inc.	10	150
71288-0728-32	J0665	Meitheal Pharmaceuticals Inc.	30	450
71351-0022-10	J0665	Brookfield Pharmaceuticals, LLC	10 × 2	300
72266-0263-10	J0665	Fosun Pharma Usa Inc.	10 × 10	500
72266-0264-10	J0665	Fosun Pharma Usa Inc.	10 × 10	1000
72603-0279-25	J0665	Northstar RxLLC	25 × 50	6250
72603-0287-25	J0665	Northstar RxLLC	25 × 50	12500
72603-0327-25	J0665	Northstar RxLLC	25 × 10	1250
72603-0506-10	J0665	Northstar RxLLC	10 × 10	1000
72603-0506-25	J0665	Northstar RxLLC	25 × 10	2500
72603-0700-10	J0665	Northstar RxLLC	10 × 10	1500
72603-0700-25	J0665	Northstar RxLLC	25 × 10	3750
72603-0800-25	J0665	Northstar RxLLC	25 × 30	11250

Bupivacaine HCl: common questions

What is the J-code for Bupivacaine HCl?: Bupivacaine HCl is billed under HCPCS J0665 — Injection, bupivicaine, not otherwise specified, 0.5 mg. One billing unit is 0.5 mg. CMS's crosswalk lists 61 Bupivacaine HCl NDCs under this code.
How many J0665 billing units are in a package of Bupivacaine HCl?: CMS lists 50 to 12,500 billing units per package, depending on the NDC, where one unit is 0.5 mg. Units to report are based on the dose given, not the package.
Is J0665 a CPT code?: No. J0665 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Bupivacaine HCl J-Code / HCPCS Code