No. J0665 is a HCPCS Level II code, maintained by CMS, that identifies a drug with no specific code of its own. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDC goes with J0665?

None is fixed. J0665 is used for drugs that have no specific HCPCS code, so the claim carries the NDC of the drug actually given and its quantity, and payers usually also ask for the drug name and dose.

What is the Medicare payment limit for J0665?

$0.01 per 0.5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J0665 J-Code: Bupivicaine — Billing Units & NDCs

In short

J0665 is the HCPCS Level II code for injection, bupivicaine, not otherwise specified, 0.5 mg: drugs with no specific code of their own. It has no fixed drug or unit, so the claim carries the NDC of the drug given and its quantity.

Code

CMS HCPCS file

HCPCS codeJ0665

Billing unit0.5 mg

Descriptor: Injection, bupivicaine, not otherwise specified, 0.5 mg
Short descriptor: Inj, bupivacaine, nos, 0.5mg
Code set: HCPCS Level II, maintained by CMS
Effective: Jan 1, 2024

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$0.01

Per0.5 mg

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

NDCs billed under J0665

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 99 NDCs to J0665 for Bupivacaine HCl, Bupivicaine, Marcaine, Marcaine Spinal, Sensorcaine and Sensorcaine-MPF. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J0665 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Bupivacaine HCl	00143-9328-10	Hikma Pharmaceuticals USA Inc.	10 × 50	2,500
Bupivacaine HCl	00143-9329-10	Hikma Pharmaceuticals USA Inc.	10 × 50	5,000
Bupivacaine HCl	00143-9330-10	Hikma Pharmaceuticals USA Inc.	10 × 10	500
Bupivacaine HCl	00143-9331-10	Hikma Pharmaceuticals USA Inc.	10 × 10	1,000
Bupivacaine HCl	00143-9332-10	Hikma Pharmaceuticals USA Inc.	10 × 10	1,500
Bupivacaine HCl	00143-9333-10	Hikma Pharmaceuticals USA Inc.	10 × 30	1,500
Bupivacaine HCl	00143-9334-10	Hikma Pharmaceuticals USA Inc.	10 × 30	3,000
Bupivacaine HCl	00143-9335-10	Hikma Pharmaceuticals USA Inc.	10 × 30	4,500
Bupivacaine HCl	00404-9826-50	Henry Schein Inc.	50	250
Bupivacaine HCl	00404-9827-50	Henry Schein Inc.	50	500
Bupivacaine HCl	00409-1159-01	Pfizer Inc	25 × 10	1,250
Bupivacaine HCl	00409-1159-02	Pfizer Inc	25 × 30	3,750
Bupivacaine HCl	00409-1159-10	Pfizer Inc	25 × 30	3,750
Bupivacaine HCl	00409-1160-01	Pfizer Inc	25 × 50	6,250
Bupivacaine HCl	00409-1162-01	Pfizer Inc	25 × 10	2,500
Bupivacaine HCl	00409-1162-02	Pfizer Inc	25 × 30	7,500
Bupivacaine HCl	00409-1163-01	Pfizer Inc	25 × 50	12,500
Bupivacaine HCl	00409-1165-01	Pfizer Inc	25 × 10	3,750
Bupivacaine HCl	00409-1165-02	Pfizer Inc	25 × 30	11,250
Bupivacaine HCl	50090-4516-00	A-S Medication Solutions	50	500
Bupivacaine HCl	51662-1396-01	HF Acquisition Co. LLC, DBA HealthFirst	50	500
Bupivacaine HCl	51662-1396-03	HF Acquisition Co. LLC, DBA HealthFirst	25 × 50	12,500
Bupivacaine HCl	51662-1581-03	HF Acquisition Co. LLC, DBA HealthFirst	25 × 50	6,250
Bupivacaine HCl	52584-0465-57	Henry Schein Inc.	50	250
Bupivacaine HCl	52584-0467-57	Henry Schein Inc.	50	500
Bupivacaine HCl	55150-0167-10	Eugia US LLC	25 × 10	1,250
Bupivacaine HCl	55150-0168-30	Eugia US LLC	25 × 30	3,750
Bupivacaine HCl	55150-0169-10	Eugia US LLC	25 × 10	2,500
Bupivacaine HCl	55150-0170-30	Eugia US LLC	25 × 30	7,500
Bupivacaine HCl	55150-0171-10	Eugia US LLC	25 × 10	3,750
Bupivacaine HCl	55150-0172-30	Eugia US LLC	25 × 30	11,250
Bupivacaine HCl	55150-0249-50	Eugia US LLC	25 × 50	6,250
Bupivacaine HCl	55150-0250-50	Eugia US LLC	25 × 50	12,500
Bupivacaine HCl	70069-0752-25	Somerset Pharma, LLC	25 × 50	6,250
Bupivacaine HCl	70594-0114-02	Xellia Pharmaceuticals USA, LLC.	10 × 10	500
Bupivacaine HCl	70594-0115-01	Xellia Pharmaceuticals USA, LLC.	30	150
Bupivacaine HCl	70594-0116-01	Xellia Pharmaceuticals USA, LLC.	50	250
Bupivacaine HCl	70594-0117-02	Xellia Pharmaceuticals USA, LLC.	10 × 10	1,000
Bupivacaine HCl	70594-0118-01	Xellia Pharmaceuticals USA, LLC.	30	300
Bupivacaine HCl	70594-0119-01	Xellia Pharmaceuticals USA, LLC.	50	500
Bupivacaine HCl	70594-0120-02	Xellia Pharmaceuticals USA, LLC.	10 × 10	1,500
Bupivacaine HCl	70594-0121-01	Xellia Pharmaceuticals USA, LLC.	30	450
Bupivacaine HCl	71288-0721-11	Meitheal Pharmaceuticals Inc.	10	50
Bupivacaine HCl	71288-0722-32	Meitheal Pharmaceuticals Inc.	30	150
Bupivacaine HCl	71288-0723-52	Meitheal Pharmaceuticals Inc.	50	250
Bupivacaine HCl	71288-0724-11	Meitheal Pharmaceuticals Inc.	10	100
Bupivacaine HCl	71288-0725-32	Meitheal Pharmaceuticals Inc.	30	300
Bupivacaine HCl	71288-0726-52	Meitheal Pharmaceuticals Inc.	50	500
Bupivacaine HCl	71288-0727-11	Meitheal Pharmaceuticals Inc.	10	150
Bupivacaine HCl	71288-0728-32	Meitheal Pharmaceuticals Inc.	30	450
Bupivacaine HCl	71351-0022-10	Brookfield Pharmaceuticals, LLC	10 × 2	300
Bupivacaine HCl	72266-0263-10	Fosun Pharma Usa Inc.	10 × 10	500
Bupivacaine HCl	72266-0264-10	Fosun Pharma Usa Inc.	10 × 10	1,000
Bupivacaine HCl	72603-0279-25	Northstar RxLLC	25 × 50	6,250
Bupivacaine HCl	72603-0287-25	Northstar RxLLC	25 × 50	12,500
Bupivacaine HCl	72603-0327-25	Northstar RxLLC	25 × 10	1,250
Bupivacaine HCl	72603-0506-10	Northstar RxLLC	10 × 10	1,000
Bupivacaine HCl	72603-0506-25	Northstar RxLLC	25 × 10	2,500
Bupivacaine HCl	72603-0700-10	Northstar RxLLC	10 × 10	1,500
Bupivacaine HCl	72603-0700-25	Northstar RxLLC	25 × 10	3,750

Showing 60 of 99. The full list is in the CMS crosswalk file.

J0665: common questions

Is J0665 a CPT code?: No. J0665 is a HCPCS Level II code, maintained by CMS, that identifies a drug with no specific code of its own. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDC goes with J0665?: None is fixed. J0665 is used for drugs that have no specific HCPCS code, so the claim carries the NDC of the drug actually given and its quantity, and payers usually also ask for the drug name and dose. How to find a J-code.
What is the Medicare payment limit for J0665?: $0.01 per 0.5 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J0665 — Injection, bupivicaine, not otherwise specified, 0.5 mg