In short

Buprenorphine HCl is billed under HCPCS J0592 — Injection, buprenorphine hydrochloride, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 3 Buprenorphine HCl NDCs under this code.

J0592 code details

Reference

J0592
Injection, buprenorphine hydrochloride, 0.1 mgBilling unit: 0.1 mg
Labelers
Endo USA, Inc.; Pfizer Inc; Somerset Pharma, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$4.698
Per0.1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Buprenorphine HCl units and claim line

Enter the dose given to get the J0592 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Buprenorphine HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Buprenorphine HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-2012-32J0592Pfizer Inc10 × 130
42023-0179-05J0592Endo USA, Inc.5 × 115
70069-0027-05J0592Somerset Pharma, LLC5 × 115

Buprenorphine HCl: common questions

What is the J-code for Buprenorphine HCl?
Buprenorphine HCl is billed under HCPCS J0592 — Injection, buprenorphine hydrochloride, 0.1 mg. One billing unit is 0.1 mg. CMS's crosswalk lists 3 Buprenorphine HCl NDCs under this code.
How many J0592 billing units are in a package of Buprenorphine HCl?
CMS lists 15 to 30 billing units per package, depending on the NDC, where one unit is 0.1 mg. Units to report are based on the dose given, not the package.
Is J0592 a CPT code?
No. J0592 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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