In short

CMS assigns Daptomycin NDCs to 5 HCPCS codes: J0871 (per 1 mg), J0872 (per 1 mg), J0873 (per 1 mg), J0877 (per 1 mg), J0878 (per 1 mg). Which one applies depends on the product; the table lists each NDC with its code.

J0871 code detailsJ0872 code detailsJ0873 code detailsJ0877 code detailsJ0878 code details

Reference

J0871
Injection, daptomycin (endo), not therapeutically equivalent to j0878, 1 mgBilling unit: 1 mg
J0872
Injection, daptomycin (xellia), unrefrigerated, not therapeutically equivalent to j0878 or j0873, 1 mgBilling unit: 1 mg
J0873
Injection, daptomycin (xellia), not therapeutically equivalent to j0878 or j0872, 1 mgBilling unit: 1 mg
J0877
Injection, daptomycin (hospira), not therapeutically equivalent to j0878, 1 mgBilling unit: 1 mg
J0878
Injection, daptomycin, 1 mgBilling unit: 1 mg
Labelers
Accord Healthcare Inc; Apotex Corp; BE Pharmaceuticals Inc.; Biocon Pharma Inc; BluePoint Laboratories; Civica, Inc.; Dr. Reddy's Laboratories Inc.; Endo Usa, Inc.and 8 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.541
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.06
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.048
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.022
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.027
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Daptomycin units and claim line

Enter the dose given to get the J0871 units and the NDC line for the CMS-1500 and the 837P. This builds the J0871 line; use the code page for J0872, J0873, J0877, J0878.

Enter the dose given to build the claim line.

Daptomycin NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Daptomycin NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
42023-0295-10J0871Endo Usa, Inc.10 × 15000
00143-9445-01J0872Hikma Pharmaceuticals USA Inc.1500
70594-0060-01J0872Xellia Pharmaceuticals USA, LLC.1500
70594-0066-01J0872Xellia Pharmaceuticals USA, LLC.1350
72572-0158-01J0872Civica, Inc.1500
00143-9455-01J0873Hikma Pharmaceuticals USA Inc.1350
70594-0053-01J0873Xellia Pharmaceuticals USA, LLC.1350
72572-0100-01J0873Civica, Inc.1350
00409-0120-01J0877Pfizer Inc1350
00409-0122-01J0877Pfizer Inc1500
00143-9378-01J0878Hikma Pharmaceuticals USA Inc.1500
00143-9444-01J0878Hikma Pharmaceuticals USA Inc.1500
00143-9465-01J0878Hikma Pharmaceuticals USA Inc.1500
16714-0892-01J0878Northstar RxLLC1500
16729-0434-05J0878Accord Healthcare Inc1350
16729-0434-45J0878Accord Healthcare Inc10 × 13500
16729-0435-05J0878Accord Healthcare Inc1500
25021-0174-15J0878Sagent Pharmaceuticals1500
25021-0174-16J0878Sagent Pharmaceuticals10 × 15000
25021-0179-15J0878Sagent Pharmaceuticals1350
25021-0179-16J0878Sagent Pharmaceuticals10 × 13500
25021-0179-66J0878Sagent Pharmaceuticals1350
25021-0179-67J0878Sagent Pharmaceuticals10 × 13500
43598-0413-11J0878Dr. Reddy's Laboratories Inc.1500
43598-0476-11J0878Dr. Reddy's Laboratories Inc.1350
55150-0344-01J0878Eugia US LLC1500
60505-6229-04J0878Apotex Corp1500
67457-0813-50J0878Mylan Institutional LLC1500
67457-0941-15J0878Mylan Institutional LLC1500
68001-0376-68J0878BluePoint Laboratories1500
70377-0093-91J0878Biocon Pharma Inc1500
70594-0034-01J0878Xellia Pharmaceuticals USA, LLC.1500
70594-0034-02J0878Xellia Pharmaceuticals USA, LLC.1500
71288-0016-15J0878Meitheal Pharmaceuticals Inc.1500
71288-0016-91J0878Meitheal Pharmaceuticals Inc.1500
71288-0016-95J0878Meitheal Pharmaceuticals Inc.1500
71288-0017-15J0878Meitheal Pharmaceuticals Inc.1350
71288-0017-91J0878Meitheal Pharmaceuticals Inc.1350
71839-0107-01J0878BE Pharmaceuticals Inc.1500
71839-0108-01J0878BE Pharmaceuticals Inc.1350
72572-0102-01J0878Civica, Inc.1500
72603-0147-01J0878Northstar RxLLC1350
72603-0152-01J0878Northstar RxLLC1500

Daptomycin: common questions

What is the J-code for Daptomycin?
CMS assigns Daptomycin NDCs to 5 HCPCS codes: J0871 (per 1 mg), J0872 (per 1 mg), J0873 (per 1 mg), J0877 (per 1 mg), J0878 (per 1 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J0871 billing units are in a package of Daptomycin?
CMS lists 5,000 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J0872 billing units are in a package of Daptomycin?
CMS lists 350 to 500 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J0873 billing units are in a package of Daptomycin?
CMS lists 350 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J0877 billing units are in a package of Daptomycin?
CMS lists 350 to 500 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J0878 billing units are in a package of Daptomycin?
CMS lists 350 to 5,000 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
Is J0871 a CPT code?
No. J0871 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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