HCPCS Level II drug code
J0878 — Injection, daptomycin, 1 mg
In short
J0878 is the HCPCS Level II code for injection, daptomycin, 1 mg. CMS assigns NDCs for Daptomycin to it. One billing unit is 1 mg. The Medicare Part B payment limit is $0.027 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, daptomycin, 1 mg
- Short descriptor
- Daptomycin injection
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 2024
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: AMP-based payment limit. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J0878
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 33 NDCs to J0878 for Daptomycin. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Daptomycin | 00143-9378-01 | Hikma Pharmaceuticals USA Inc. | 1 | 500 |
| Daptomycin | 00143-9444-01 | Hikma Pharmaceuticals USA Inc. | 1 | 500 |
| Daptomycin | 00143-9465-01 | Hikma Pharmaceuticals USA Inc. | 1 | 500 |
| Daptomycin | 16714-0892-01 | Northstar RxLLC | 1 | 500 |
| Daptomycin | 16729-0434-05 | Accord Healthcare Inc | 1 | 350 |
| Daptomycin | 16729-0434-45 | Accord Healthcare Inc | 10 × 1 | 3,500 |
| Daptomycin | 16729-0435-05 | Accord Healthcare Inc | 1 | 500 |
| Daptomycin | 25021-0174-15 | Sagent Pharmaceuticals | 1 | 500 |
| Daptomycin | 25021-0174-16 | Sagent Pharmaceuticals | 10 × 1 | 5,000 |
| Daptomycin | 25021-0179-15 | Sagent Pharmaceuticals | 1 | 350 |
| Daptomycin | 25021-0179-16 | Sagent Pharmaceuticals | 10 × 1 | 3,500 |
| Daptomycin | 25021-0179-66 | Sagent Pharmaceuticals | 1 | 350 |
| Daptomycin | 25021-0179-67 | Sagent Pharmaceuticals | 10 × 1 | 3,500 |
| Daptomycin | 43598-0413-11 | Dr. Reddy's Laboratories Inc. | 1 | 500 |
| Daptomycin | 43598-0476-11 | Dr. Reddy's Laboratories Inc. | 1 | 350 |
| Daptomycin | 55150-0344-01 | Eugia US LLC | 1 | 500 |
| Daptomycin | 60505-6229-04 | Apotex Corp | 1 | 500 |
| Daptomycin | 67457-0813-50 | Mylan Institutional LLC | 1 | 500 |
| Daptomycin | 67457-0941-15 | Mylan Institutional LLC | 1 | 500 |
| Daptomycin | 68001-0376-68 | BluePoint Laboratories | 1 | 500 |
| Daptomycin | 70377-0093-91 | Biocon Pharma Inc | 1 | 500 |
| Daptomycin | 70594-0034-01 | Xellia Pharmaceuticals USA, LLC. | 1 | 500 |
| Daptomycin | 70594-0034-02 | Xellia Pharmaceuticals USA, LLC. | 1 | 500 |
| Daptomycin | 71288-0016-15 | Meitheal Pharmaceuticals Inc. | 1 | 500 |
| Daptomycin | 71288-0016-91 | Meitheal Pharmaceuticals Inc. | 1 | 500 |
| Daptomycin | 71288-0016-95 | Meitheal Pharmaceuticals Inc. | 1 | 500 |
| Daptomycin | 71288-0017-15 | Meitheal Pharmaceuticals Inc. | 1 | 350 |
| Daptomycin | 71288-0017-91 | Meitheal Pharmaceuticals Inc. | 1 | 350 |
| Daptomycin | 71839-0107-01 | BE Pharmaceuticals Inc. | 1 | 500 |
| Daptomycin | 71839-0108-01 | BE Pharmaceuticals Inc. | 1 | 350 |
| Daptomycin | 72572-0102-01 | Civica, Inc. | 1 | 500 |
| Daptomycin | 72603-0147-01 | Northstar RxLLC | 1 | 350 |
| Daptomycin | 72603-0152-01 | Northstar RxLLC | 1 | 500 |
J0878: common questions
- Is J0878 a CPT code?
- No. J0878 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J0878?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 33 NDCs under J0878, for Daptomycin. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J0878?
- $0.027 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J0878?
- One unit of J0878 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.