In short

CMS assigns Emend NDCs to 2 HCPCS codes: J1453 (per 1 mg), J8501 (per 5 mg). Which one applies depends on the product; the table lists each NDC with its code.

J1453 code detailsJ8501 code details

Reference

J1453
Injection, fosaprepitant, 1 mgBilling unit: 1 mg
J8501
Aprepitant, oral, 5 mgBilling unit: 5 mg
Labelers
Merck Sharp & Dohme LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.114
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.511
Per5 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Emend units and claim line

Enter the dose given to get the J1453 units and the NDC line for the CMS-1500 and the 837P. This builds the J1453 line; use the code page for J8501.

Enter the dose given to build the claim line.

Emend NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Emend NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00006-3061-00J1453Merck Sharp & Dohme LLC1150
00006-0461-02J8501Merck Sharp & Dohme LLC2 × 132
00006-3066-03J8501Merck Sharp & Dohme LLC125
00006-3862-03J8501Merck Sharp & Dohme LLC3 × 157

Emend: common questions

What is the J-code for Emend?
CMS assigns Emend NDCs to 2 HCPCS codes: J1453 (per 1 mg), J8501 (per 5 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J1453 billing units are in a package of Emend?
CMS lists 150 billing units per package, depending on the NDC, where one unit is 1 mg. Units to report are based on the dose given, not the package.
How many J8501 billing units are in a package of Emend?
CMS lists 25 to 57 billing units per package, depending on the NDC, where one unit is 5 mg. Units to report are based on the dose given, not the package.
Is J1453 a CPT code?
No. J1453 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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