In short

J1453 is the HCPCS Level II code for injection, fosaprepitant, 1 mg. CMS assigns NDCs for Emend and Fosaprepitant to it. One billing unit is 1 mg. The Medicare Part B payment limit is $0.114 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ1453
Billing unit1 mg
Descriptor
Injection, fosaprepitant, 1 mg
Short descriptor
Fosaprepitant injection
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2022

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.114
Per1 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Units = dose given ÷ 1 mg. For example, 100 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

NDCs billed under J1453

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 22 NDCs to J1453 for Emend and Fosaprepitant. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J1453 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Emend00006-3061-00Merck Sharp & Dohme LLC1150
Fosaprepitant00143-9384-01Hikma Pharmaceuticals USA Inc.1150
Fosaprepitant00143-9428-01Hikma Pharmaceuticals USA Inc.1150
Fosaprepitant16714-0248-01Northstar RxLLC1150
Fosaprepitant43598-0859-11Dr. Reddy's Laboratories Inc.1150
Fosaprepitant43598-0948-11Dr. Reddy's Laboratories Inc.1150
Fosaprepitant55150-0299-01Eugia US LLC1150
Fosaprepitant60505-6105-01Apotex Corp1150
Fosaprepitant63323-0972-10FreseniUS Kabi USA, LLC1150
Fosaprepitant67457-0889-10Mylan Institutional LLC1150
Fosaprepitant68001-0523-36BluePoint Laboratories1150
Fosaprepitant68001-0675-25Bluepoint Laboratories1150
Fosaprepitant70860-0780-10Athenex Pharmaceutical Division, LLC1150
Fosaprepitant70860-0782-10Athenex Pharmaceutical Division, LLC1150
Fosaprepitant70860-0783-10Athenex Pharmaceutical Division, LLC1150
Fosaprepitant71839-0104-01BE Pharmaceuticals Inc.1150
Fosaprepitant72205-0026-01Novadoz Pharmaceuticals LLC1150
Fosaprepitant72205-0054-01Novadoz Pharmaceuticals LLC1150
Fosaprepitant72205-0083-01Novadoz Pharmaceuticals LLC1150
Fosaprepitant72603-0450-01Northstar RxLLC1150
Fosaprepitant81952-0911-01Hepalink USA, Inc.1150
Fosaprepitant83634-0776-10Avenacy Inc.1150

J1453: common questions

Is J1453 a CPT code?
No. J1453 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J1453?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 22 NDCs under J1453, for Emend and Fosaprepitant. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J1453?
$0.114 per 1 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
What is one billing unit of J1453?
One unit of J1453 is 1 mg, as stated in the code's descriptor. Units to report = dose given ÷ 1 mg. J-code billing units.

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