In short

Epioxa HD/Epioxa is billed under HCPCS J2789 — Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml. One billing unit is up to 2 ml. CMS's crosswalk lists 1 Epioxa HD/Epioxa NDC under this code.

J2789 code details

Reference

J2789
Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 mlBilling unit: up to 2 ml
Labelers
Glaukos Corporation

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$41,359.618
Perup to 2 ml
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Epioxa HD/Epioxa units and claim line

Enter the dose given to get the J2789 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Epioxa HD/Epioxa NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Epioxa HD/Epioxa NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
25357-0024-01J2789Glaukos Corporation2 × 22

Epioxa HD/Epioxa: common questions

What is the J-code for Epioxa HD/Epioxa?
Epioxa HD/Epioxa is billed under HCPCS J2789 — Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml. One billing unit is up to 2 ml. CMS's crosswalk lists 1 Epioxa HD/Epioxa NDC under this code.
How many J2789 billing units are in a package of Epioxa HD/Epioxa?
CMS lists 2 billing units per package, depending on the NDC, where one unit is up to 2 ml. Units to report are based on the dose given, not the package.
Is J2789 a CPT code?
No. J2789 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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