No. J2789 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code.

What NDCs are billed under J2789?

CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J2789, for Epioxa HD/Epioxa. The table on this page shows each one with its billing units per package.

What is the Medicare payment limit for J2789?

$41,359.618 per up to 2 ml, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J2789 J-Code: Epioxa HD/Epioxa (riboflavin 5'-phosphate)

In short

J2789 is the HCPCS Level II code for riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml. CMS assigns NDCs for Epioxa HD/Epioxa to it. The Medicare Part B payment limit is $41,359.618 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file

HCPCS codeJ2789

Billing unitSee descriptor

Descriptor: Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml
Short descriptor: Riboflavin epioxa/hd<=2ml
Code set: HCPCS Level II, maintained by CMS
Effective: Jul 1, 2026

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$41,359.618

Perup to 2 ml

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. CMS note: Added October 2026. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

NDCs billed under J2789

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 1 NDC to J2789 for Epioxa HD/Epioxa. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J2789 in the CMS ASP crosswalk
Drug	NDC (11-digit)	Labeler	Package	Billing units per package
Epioxa HD/Epioxa	25357-0024-01	Glaukos Corporation	2 × 2	2

J2789: common questions

Is J2789 a CPT code?: No. J2789 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J2789?: CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 1 NDC under J2789, for Epioxa HD/Epioxa. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J2789?: $41,359.618 per up to 2 ml, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

J2789 — Riboflavin 5'-phosphate, ophthalmic solution (epioxahd/epioxa), up to 2 ml