In short

CMS assigns Epogen NDCs to 2 HCPCS codes: J0885 (per 1000 units), Q4081 (per 100 units). Which one applies depends on the product; the table lists each NDC with its code.

J0885 code detailsQ4081 code details

Reference

J0885
Injection, epoetin alfa, (for non-esrd use), 1000 unitsBilling unit: 1000 units
Q4081
HCPCS Level II drug codeBilling unit: 100 units
Labelers
Amgen Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$6.669
Per1000 units
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$0.667
Per100 units
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Epogen units and claim line

Enter the dose given to get the J0885 units and the NDC line for the CMS-1500 and the 837P. This builds the J0885 line; use the code page for Q4081.

Enter the dose given to build the claim line.

Epogen NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Epogen NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
55513-0126-10J0885Amgen Inc10 × 120
55513-0126-20J0885Amgen Inc10 × 120
55513-0144-10J0885Amgen Inc10 × 1100
55513-0148-10J0885Amgen Inc10 × 140
55513-0267-10J0885Amgen Inc10 × 130
55513-0267-20J0885Amgen Inc10 × 130
55513-0283-10J0885Amgen Inc10 × 2200
55513-0283-20J0885Amgen Inc10 × 2200
55513-0478-10J0885Amgen Inc10 × 1200
55513-0478-20J0885Amgen Inc10 × 1200
55513-0126-10Q4081Amgen Inc10 × 1200
55513-0126-20Q4081Amgen Inc10 × 1200
55513-0144-10Q4081Amgen Inc10 × 11000
55513-0148-10Q4081Amgen Inc10 × 1400
55513-0267-10Q4081Amgen Inc10 × 1300
55513-0267-20Q4081Amgen Inc10 × 1300
55513-0283-10Q4081Amgen Inc10 × 22000
55513-0283-20Q4081Amgen Inc10 × 22000
55513-0478-10Q4081Amgen Inc10 × 12000
55513-0478-20Q4081Amgen Inc10 × 12000

Epogen: common questions

What is the HCPCS code for Epogen?
CMS assigns Epogen NDCs to 2 HCPCS codes: J0885 (per 1000 units), Q4081 (per 100 units). Which one applies depends on the product; the table lists each NDC with its code.
How many J0885 billing units are in a package of Epogen?
CMS lists 20 to 200 billing units per package, depending on the NDC, where one unit is 1000 units. Units to report are based on the dose given, not the package.
How many Q4081 billing units are in a package of Epogen?
CMS lists 200 to 2,000 billing units per package, depending on the NDC, where one unit is 100 units. Units to report are based on the dose given, not the package.
Is J0885 a CPT code?
No. J0885 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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