In short

Esperoct is billed under HCPCS J7204 — Injection, factor viii, antihemophilic factor (recombinant), (esperoct), glycopegylated-exei, per iu. One billing unit is 1 IU. CMS's crosswalk lists 6 Esperoct NDCs under this code.

J7204 code details

Reference

J7204
Injection, factor viii, antihemophilic factor (recombinant), (esperoct), glycopegylated-exei, per iuBilling unit: 1 IU
Labelers
Novo Nordisk, Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$2.363
Per1 iu
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Esperoct units and claim line

Enter the dose given to get the J7204 units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

Esperoct NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Esperoct NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00169-8100-01J7204Novo Nordisk, Inc11
00169-8150-01J7204Novo Nordisk, Inc11
00169-8200-01J7204Novo Nordisk, Inc11
00169-8300-01J7204Novo Nordisk, Inc11
00169-8400-01J7204Novo Nordisk, Inc11
00169-8500-01J7204Novo Nordisk, Inc11

Esperoct: common questions

What is the J-code for Esperoct?
Esperoct is billed under HCPCS J7204 — Injection, factor viii, antihemophilic factor (recombinant), (esperoct), glycopegylated-exei, per iu. One billing unit is 1 IU. CMS's crosswalk lists 6 Esperoct NDCs under this code.
How many J7204 billing units are in a package of Esperoct?
CMS lists 1 billing units per package, depending on the NDC, where one unit is 1 IU. Units to report are based on the dose given, not the package.
Is J7204 a CPT code?
No. J7204 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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