HCPCS drug code · CMS crosswalk
Estradiol Valerate J-Code / HCPCS Code
In short
Estradiol Valerate is billed under HCPCS J1380 — Injection, estradiol valerate, up to 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 10 Estradiol Valerate NDCs under this code.
Reference
- J1380
- Injection, estradiol valerate, up to 10 mgBilling unit: 10 mg
- Labelers
- American Regent, Inc.; Hikma Pharmaceuticals USA Inc.; Padagis US LLC; Xiromed, LLC
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Estradiol Valerate units and claim line
Enter the dose given to get the J1380 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Estradiol Valerate NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00143-9289-01 | J1380 | Hikma Pharmaceuticals USA Inc. | 5 | 5 |
| 00143-9290-01 | J1380 | Hikma Pharmaceuticals USA Inc. | 5 | 10 |
| 00143-9291-01 | J1380 | Hikma Pharmaceuticals USA Inc. | 5 | 20 |
| 00517-0420-01 | J1380 | American Regent, Inc. | 5 | 10 |
| 00517-0440-01 | J1380 | American Regent, Inc. | 5 | 20 |
| 00574-0870-05 | J1380 | Padagis US LLC | 5 | 10 |
| 00574-0872-05 | J1380 | Padagis US LLC | 5 | 20 |
| 70700-0273-22 | J1380 | Xiromed, LLC | 5 | 5 |
| 70700-0274-22 | J1380 | Xiromed, LLC | 5 | 10 |
| 70700-0275-22 | J1380 | Xiromed, LLC | 5 | 20 |
Estradiol Valerate: common questions
- What is the J-code for Estradiol Valerate?
- Estradiol Valerate is billed under HCPCS J1380 — Injection, estradiol valerate, up to 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 10 Estradiol Valerate NDCs under this code.
- How many J1380 billing units are in a package of Estradiol Valerate?
- CMS lists 5 to 20 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
- Is J1380 a CPT code?
- No. J1380 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.