How many J7321 billing units are in a package of Hyalgan?

CMS lists 1 billing units per package, depending on the NDC, where one unit is per dose. Units to report are based on the dose given, not the package.

No. J7321 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Hyalgan J-Code J7321 — Billing Units & NDCs

In short

Hyalgan is billed under HCPCS J7321 — Hyaluronan or derivative, hyalgan, supartz or visco-3, for intra-articular injection, per dose. One billing unit is per dose. CMS's crosswalk lists 2 Hyalgan NDCs under this code.

J7321 code details

Reference

J7321: Hyaluronan or derivative, hyalgan, supartz or visco-3, for intra-articular injection, per doseBilling unit: per dose
Labelers: Fidia Pharma USA Inc

Medicare Part B payment limit

CMS ASP file

Payment limit per unit$69.868

Perper dose

Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Hyalgan units and claim line

Enter the dose given to get the J7321 units and the NDC line for the CMS-1500 and the 837P.

HCPCS units

Modifier

NDC (11-digit)

NDC unit qualifier

NDC quantity

Enter the units to build the claim line.

Hyalgan NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Hyalgan NDCs in the CMS ASP crosswalk
NDC (11-digit)	HCPCS	Labeler	Package	Billing units per package
89122-0724-12	J7321	Fidia Pharma USA Inc	2	1
89122-0724-20	J7321	Fidia Pharma USA Inc	2	1

Hyalgan: common questions

What is the J-code for Hyalgan?: Hyalgan is billed under HCPCS J7321 — Hyaluronan or derivative, hyalgan, supartz or visco-3, for intra-articular injection, per dose. One billing unit is per dose. CMS's crosswalk lists 2 Hyalgan NDCs under this code.
How many J7321 billing units are in a package of Hyalgan?: CMS lists 1 billing units per package, depending on the NDC, where one unit is per dose. Units to report are based on the dose given, not the package.
Is J7321 a CPT code?: No. J7321 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

Hyalgan J-Code / HCPCS Code