In short

J7321 is the HCPCS Level II code for hyaluronan or derivative, hyalgan, supartz or visco-3, for intra-articular injection, per dose. CMS assigns NDCs for Hyalgan, Supartz FX and Visco-3 to it. The Medicare Part B payment limit is $69.868 per unit (October 1, 2026 through December 31, 2026).

Code

CMS HCPCS file
HCPCS codeJ7321
Billing unitSee descriptor
Descriptor
Hyaluronan or derivative, hyalgan, supartz or visco-3, for intra-articular injection, per dose
Short descriptor
Hyalgan supartz visco-3 dose
Code set
HCPCS Level II, maintained by CMS
Effective
Jan 1, 2024

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$69.868
Perper dose
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J7321

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 4 NDCs to J7321 for Hyalgan, Supartz FX and Visco-3. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J7321 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Hyalgan89122-0724-12Fidia Pharma USA Inc21
Hyalgan89122-0724-20Fidia Pharma USA Inc21
Supartz FX89130-4444-01Bioventus LLC2.51
Visco-350016-0957-21Zimmer Biomet3 × 2.53

J7321: common questions

Is J7321 a CPT code?
No. J7321 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDCs are billed under J7321?
CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 4 NDCs under J7321, for Hyalgan, Supartz FX and Visco-3. The table on this page shows each one with its billing units per package.
What is the Medicare payment limit for J7321?
$69.868 per per dose, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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