HCPCS drug code · CMS crosswalk
Mannitol J-Code / HCPCS Code
In short
Mannitol is billed under HCPCS J2151 — Injection, mannitol, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 7 Mannitol NDCs under this code.
Reference
- J2151
- Injection, mannitol, 250 mgBilling unit: 250 mg
- Labelers
- FreseniUS Kabi USA, LLC; HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; ICu Medical Inc.; Pfizer Inc
Medicare Part B payment limit
CMS ASP filePayment limit per unit$0.112
Per250 mg
Coinsurance20%
Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Mannitol units and claim line
Enter the dose given to get the J2151 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Mannitol NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00404-9905-50 | J2151 | Henry Schein Inc. | 50 | 50 |
| 00409-4031-01 | J2151 | Pfizer Inc | 25 × 50 | 1250 |
| 00990-7715-02 | J2151 | ICu Medical Inc. | 24 × 250 | 4800 |
| 00990-7715-03 | J2151 | ICu Medical Inc. | 12 × 500 | 4800 |
| 51662-1468-01 | J2151 | HF Acquisition Co. LLC, DBA HealthFirst | 50 | 50 |
| 51662-1468-03 | J2151 | HF Acquisition Co. LLC, DBA HealthFirst | 25 × 50 | 1250 |
| 63323-0024-25 | J2151 | FreseniUS Kabi USA, LLC | 25 × 50 | 50 |
Mannitol: common questions
- What is the J-code for Mannitol?
- Mannitol is billed under HCPCS J2151 — Injection, mannitol, 250 mg. One billing unit is 250 mg. CMS's crosswalk lists 7 Mannitol NDCs under this code.
- How many J2151 billing units are in a package of Mannitol?
- CMS lists 50 to 4,800 billing units per package, depending on the NDC, where one unit is 250 mg. Units to report are based on the dose given, not the package.
- Is J2151 a CPT code?
- No. J2151 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.