In short

Melphalan is billed under HCPCS J9245 — Injection, melphalan hydrochloride, not otherwise specified, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 13 Melphalan NDCs under this code.

J9245 code details

Reference

J9245
Injection, melphalan hydrochloride, not otherwise specified, 50 mgBilling unit: 50 mg
Labelers
Actavis Pharma, Inc.; Athenex Pharmaceutical Division, LLC; Avenacy Inc.; Dr. Reddy's Laboratories Inc.; Fosun Pharma USA Inc.; FreseniUS Kabi USA, LLC; Heritage Pharmaceuticals Inc.; Meitheal Pharmaceuticals Inc.and 3 more

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$90.032
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Melphalan units and claim line

Enter the dose given to get the J9245 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Melphalan NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Melphalan NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
23155-0355-41J9245Heritage Pharmaceuticals Inc.11
25021-0258-61J9245Sagent Pharmaceuticals11
43598-0392-48J9245Dr. Reddy's Laboratories Inc.11
45963-0686-02J9245Actavis Pharma, Inc.11
63323-0760-20J9245FreseniUS Kabi USA, LLC11
67457-0195-01J9245Mylan Institutional LLC11
67457-0215-01J9245Mylan Institutional LLC11
70700-0278-97J9245Xiromed, LLC11
70860-0214-61J9245Athenex Pharmaceutical Division, LLC11
71288-0132-90J9245Meitheal Pharmaceuticals Inc.11
72266-0128-01J9245Fosun Pharma USA Inc.11
75907-0112-11J9245Dr. Reddy's Laboratories Inc.11
83634-0202-61J9245Avenacy Inc.11

Melphalan: common questions

What is the J-code for Melphalan?
Melphalan is billed under HCPCS J9245 — Injection, melphalan hydrochloride, not otherwise specified, 50 mg. One billing unit is 50 mg. CMS's crosswalk lists 13 Melphalan NDCs under this code.
How many J9245 billing units are in a package of Melphalan?
CMS lists 1 billing units per package, depending on the NDC, where one unit is 50 mg. Units to report are based on the dose given, not the package.
Is J9245 a CPT code?
No. J9245 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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