In short

J9245 is the HCPCS Level II code for injection, melphalan hydrochloride, not otherwise specified, 50 mg: drugs with no specific code of their own. It has no fixed drug or unit, so the claim carries the NDC of the drug given and its quantity.

Code

CMS HCPCS file
HCPCS codeJ9245
Billing unit50 mg
Descriptor
Injection, melphalan hydrochloride, not otherwise specified, 50 mg
Short descriptor
Inj melpha hydroch nos 50 mg
Code set
HCPCS Level II, maintained by CMS
Effective
Jul 1, 2020

The billing unit is read from the descriptor. Confirm it against the CMS file before billing.

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$90.032
Per50 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Units and claim line

Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.

Enter the units to build the claim line.

NDCs billed under J9245

CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 13 NDCs to J9245 for Melphalan. Billing units per package are CMS’s figures for this code’s unit.

NDCs assigned to J9245 in the CMS ASP crosswalk
DrugNDC (11-digit)LabelerPackageBilling units per package
Melphalan23155-0355-41Heritage Pharmaceuticals Inc.11
Melphalan25021-0258-61Sagent Pharmaceuticals11
Melphalan43598-0392-48Dr. Reddy's Laboratories Inc.11
Melphalan45963-0686-02Actavis Pharma, Inc.11
Melphalan63323-0760-20FreseniUS Kabi USA, LLC11
Melphalan67457-0195-01Mylan Institutional LLC11
Melphalan67457-0215-01Mylan Institutional LLC11
Melphalan70700-0278-97Xiromed, LLC11
Melphalan70860-0214-61Athenex Pharmaceutical Division, LLC11
Melphalan71288-0132-90Meitheal Pharmaceuticals Inc.11
Melphalan72266-0128-01Fosun Pharma USA Inc.11
Melphalan75907-0112-11Dr. Reddy's Laboratories Inc.11
Melphalan83634-0202-61Avenacy Inc.11

J9245: common questions

Is J9245 a CPT code?
No. J9245 is a HCPCS Level II code, maintained by CMS, that identifies a drug with no specific code of its own. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
What NDC goes with J9245?
None is fixed. J9245 is used for drugs that have no specific HCPCS code, so the claim carries the NDC of the drug actually given and its quantity, and payers usually also ask for the drug name and dose. How to find a J-code.
What is the Medicare payment limit for J9245?
$90.032 per 50 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.

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