In short

Mitigo is billed under HCPCS J2274 — Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Mitigo NDCs under this code.

J2274 code details

Reference

J2274
Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mgBilling unit: 10 mg
Labelers
Piramal Critical Care Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$16.044
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Mitigo units and claim line

Enter the dose given to get the J2274 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Mitigo NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Mitigo NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
66794-0160-02J2274Piramal Critical Care Inc2020
66794-0162-02J2274Piramal Critical Care Inc2050

Mitigo: common questions

What is the J-code for Mitigo?
Mitigo is billed under HCPCS J2274 — Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 2 Mitigo NDCs under this code.
How many J2274 billing units are in a package of Mitigo?
CMS lists 20 to 50 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J2274 a CPT code?
No. J2274 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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