HCPCS Level II drug code
J2274 — Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg
In short
J2274 is the HCPCS Level II code for injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg. CMS assigns NDCs for Duramorph, Infumorph 200, Infumorph 500 and Mitigo and 1 more to it. One billing unit is 10 mg. The Medicare Part B payment limit is $16.044 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mg
- Short descriptor
- Inj morphine pf epid ithc
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 2018
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 10 mg. For example, 1000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J2274
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 8 NDCs to J2274 for Duramorph, Infumorph 200, Infumorph 500, Mitigo and Morphine Sulfate. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Duramorph | 00641-6019-10 | Hikma Pharmaceuticals USA Inc. | 10 × 10 | 10 |
| Duramorph | 00641-6020-10 | Hikma Pharmaceuticals USA Inc. | 10 × 10 | 5 |
| Infumorph 200 | 00641-6039-01 | Hikma Pharmaceuticals USA Inc. | 20 | 20 |
| Infumorph 500 | 00641-6040-01 | Hikma Pharmaceuticals USA Inc. | 20 | 50 |
| Mitigo | 66794-0160-02 | Piramal Critical Care Inc | 20 | 20 |
| Mitigo | 66794-0162-02 | Piramal Critical Care Inc | 20 | 50 |
| Morphine Sulfate | 00409-3814-12 | Pfizer Inc | 5 × 10 | 3 |
| Morphine Sulfate | 00409-3815-12 | Pfizer Inc | 5 × 10 | 5 |
J2274: common questions
- Is J2274 a CPT code?
- No. J2274 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J2274?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 8 NDCs under J2274, for Duramorph, Infumorph 200, Infumorph 500, Mitigo and Morphine Sulfate. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J2274?
- $16.044 per 10 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J2274?
- One unit of J2274 is 10 mg, as stated in the code's descriptor. Units to report = dose given ÷ 10 mg. J-code billing units.