In short

CMS assigns Morphine Sulfate NDCs to 3 HCPCS codes: J2270 (per 10 mg), J2272 (per 10 mg), J2274 (per 10 mg). Which one applies depends on the product; the table lists each NDC with its code.

J2270 code detailsJ2272 code detailsJ2274 code details

Reference

J2270
Injection, morphine sulfate, up to 10 mgBilling unit: 10 mg
J2272
Injection, morphine sulfate (fresenius kabi), not therapeutically equivalent to j2270, up to 10 mgBilling unit: 10 mg
J2274
Injection, morphine sulfate, preservative-free for epidural or intrathecal use, 10 mgBilling unit: 10 mg
Labelers
Civica, Inc.; FreseniUS Kabi USA, LLC; Hikma Pharmaceuticals USA Inc.; Pfizer Inc

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$7.259
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$9.406
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$16.044
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Morphine Sulfate units and claim line

Enter the dose given to get the J2270 units and the NDC line for the CMS-1500 and the 837P. This builds the J2270 line; use the code page for J2272, J2274.

Enter the dose given to build the claim line.

Morphine Sulfate NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Morphine Sulfate NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00409-1134-03J2270Pfizer Inc20100
00409-1134-05J2270Pfizer Inc50250
00409-1890-01J2270Pfizer Inc10 × 12
00409-1890-23J2270Pfizer Inc10 × 12
00409-1891-01J2270Pfizer Inc10 × 14
00409-1891-23J2270Pfizer Inc10 × 14
00409-1892-01J2270Pfizer Inc10 × 18
00409-1893-01J2270Pfizer Inc10 × 110
00409-1893-23J2270Pfizer Inc10 × 110
00409-1896-20J2270Pfizer Inc20100
00409-2022-01J2270Pfizer Inc50250
00641-6125-25J2270Hikma Pharmaceuticals USA Inc.25 × 110
00641-6126-25J2270Hikma Pharmaceuticals USA Inc.25 × 120
00641-6127-25J2270Hikma Pharmaceuticals USA Inc.25 × 125
00641-6191-10J2270Hikma Pharmaceuticals USA Inc.10 × 12
00641-6192-10J2270Hikma Pharmaceuticals USA Inc.10 × 14
72572-0440-25J2270Civica, Inc.25 × 110
63323-0451-01J2272FreseniUS Kabi USA, LLC25 × 125
63323-0452-01J2272FreseniUS Kabi USA, LLC25 × 15
63323-0454-01J2272FreseniUS Kabi USA, LLC25 × 110
63323-0455-01J2272FreseniUS Kabi USA, LLC25 × 113
76045-0004-11J2272FreseniUS Kabi USA, LLC10 × 12
76045-0005-11J2272FreseniUS Kabi USA, LLC10 × 14
00409-3814-12J2274Pfizer Inc5 × 103
00409-3815-12J2274Pfizer Inc5 × 105

Morphine Sulfate: common questions

What is the J-code for Morphine Sulfate?
CMS assigns Morphine Sulfate NDCs to 3 HCPCS codes: J2270 (per 10 mg), J2272 (per 10 mg), J2274 (per 10 mg). Which one applies depends on the product; the table lists each NDC with its code.
How many J2270 billing units are in a package of Morphine Sulfate?
CMS lists 2 to 250 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
How many J2272 billing units are in a package of Morphine Sulfate?
CMS lists 2 to 25 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
How many J2274 billing units are in a package of Morphine Sulfate?
CMS lists 3 to 5 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J2270 a CPT code?
No. J2270 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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