In short

Nalbuphine HCl is billed under HCPCS J2300 — Injection, nalbuphine hydrochloride, per 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 16 Nalbuphine HCl NDCs under this code.

J2300 code details

Reference

J2300
Injection, nalbuphine hydrochloride, per 10 mgBilling unit: 10 mg
Labelers
HF Acquisition Co. LLC, DBA HealthFirst; Henry Schein Inc.; Pfizer Inc; Somerset Pharma, LLC

Medicare Part B payment limit

CMS ASP file
Payment limit per unit$4.071
Per10 mg
Coinsurance20%

Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files

Nalbuphine HCl units and claim line

Enter the dose given to get the J2300 units and the NDC line for the CMS-1500 and the 837P.

Enter the dose given to build the claim line.

Nalbuphine HCl NDCs and billing units

From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.

Nalbuphine HCl NDCs in the CMS ASP crosswalk
NDC (11-digit)HCPCSLabelerPackageBilling units per package
00404-9766-10J2300Henry Schein Inc.1010
00404-9767-10J2300Henry Schein Inc.1020
00404-9917-10J2300Henry Schein Inc.1020
00404-9918-01J2300Henry Schein Inc.11
00404-9919-10J2300Henry Schein Inc.1010
00409-1463-01J2300Pfizer Inc10 × 110
00409-1463-49J2300Pfizer Inc10 × 110
00409-1464-01J2300Pfizer Inc25 × 10250
00409-1465-01J2300Pfizer Inc10 × 120
00409-1467-01J2300Pfizer Inc25 × 10500
51662-1418-01J2300HF Acquisition Co. LLC, DBA HealthFirst1020
51662-1420-01J2300HF Acquisition Co. LLC, DBA HealthFirst1010
70069-0661-10J2300Somerset Pharma, LLC10 × 10100
70069-0662-10J2300Somerset Pharma, LLC10 × 10200
70069-0671-10J2300Somerset Pharma, LLC10 × 110
70069-0672-10J2300Somerset Pharma, LLC10 × 120

Nalbuphine HCl: common questions

What is the J-code for Nalbuphine HCl?
Nalbuphine HCl is billed under HCPCS J2300 — Injection, nalbuphine hydrochloride, per 10 mg. One billing unit is 10 mg. CMS's crosswalk lists 16 Nalbuphine HCl NDCs under this code.
How many J2300 billing units are in a package of Nalbuphine HCl?
CMS lists 1 to 500 billing units per package, depending on the NDC, where one unit is 10 mg. Units to report are based on the dose given, not the package.
Is J2300 a CPT code?
No. J2300 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.

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