HCPCS Level II drug code
J2300 — Injection, nalbuphine hydrochloride, per 10 mg
In short
J2300 is the HCPCS Level II code for injection, nalbuphine hydrochloride, per 10 mg. CMS assigns NDCs for Nalbuphine HCl to it. One billing unit is 10 mg. The Medicare Part B payment limit is $4.071 per unit (October 1, 2026 through December 31, 2026).
Code
CMS HCPCS file- Descriptor
- Injection, nalbuphine hydrochloride, per 10 mg
- Short descriptor
- Inj nalbuphine hydrochloride
- Code set
- HCPCS Level II, maintained by CMS
- Effective
- Jan 1, 1997
The billing unit is read from the descriptor. Confirm it against the CMS file before billing.
Medicare Part B payment limit
CMS ASP fileEffective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Units and claim line
Units = dose given ÷ 10 mg. For example, 1000 mg is 100 units. Enter the dose to get the units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
NDCs billed under J2300
CMS’s ASP NDC–HCPCS crosswalk (effective October 1, 2026 through December 31, 2026) assigns 16 NDCs to J2300 for Nalbuphine HCl. Billing units per package are CMS’s figures for this code’s unit.
| Drug | NDC (11-digit) | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| Nalbuphine HCl | 00404-9766-10 | Henry Schein Inc. | 10 | 10 |
| Nalbuphine HCl | 00404-9767-10 | Henry Schein Inc. | 10 | 20 |
| Nalbuphine HCl | 00404-9917-10 | Henry Schein Inc. | 10 | 20 |
| Nalbuphine HCl | 00404-9918-01 | Henry Schein Inc. | 1 | 1 |
| Nalbuphine HCl | 00404-9919-10 | Henry Schein Inc. | 10 | 10 |
| Nalbuphine HCl | 00409-1463-01 | Pfizer Inc | 10 × 1 | 10 |
| Nalbuphine HCl | 00409-1463-49 | Pfizer Inc | 10 × 1 | 10 |
| Nalbuphine HCl | 00409-1464-01 | Pfizer Inc | 25 × 10 | 250 |
| Nalbuphine HCl | 00409-1465-01 | Pfizer Inc | 10 × 1 | 20 |
| Nalbuphine HCl | 00409-1467-01 | Pfizer Inc | 25 × 10 | 500 |
| Nalbuphine HCl | 51662-1418-01 | HF Acquisition Co. LLC, DBA HealthFirst | 10 | 20 |
| Nalbuphine HCl | 51662-1420-01 | HF Acquisition Co. LLC, DBA HealthFirst | 10 | 10 |
| Nalbuphine HCl | 70069-0661-10 | Somerset Pharma, LLC | 10 × 10 | 100 |
| Nalbuphine HCl | 70069-0662-10 | Somerset Pharma, LLC | 10 × 10 | 200 |
| Nalbuphine HCl | 70069-0671-10 | Somerset Pharma, LLC | 10 × 1 | 10 |
| Nalbuphine HCl | 70069-0672-10 | Somerset Pharma, LLC | 10 × 1 | 20 |
J2300: common questions
- Is J2300 a CPT code?
- No. J2300 is a HCPCS Level II code, maintained by CMS, that identifies the drug supplied. CPT codes are five-digit numbers from the AMA that describe services. Giving the drug, for example an injection or infusion, is usually reported with a separate CPT administration code. CPT codes for drug administration.
- What NDCs are billed under J2300?
- CMS's ASP crosswalk for October 1, 2026 through December 31, 2026 lists 16 NDCs under J2300, for Nalbuphine HCl. The table on this page shows each one with its billing units per package.
- What is the Medicare payment limit for J2300?
- $4.071 per 10 mg, effective October 1, 2026 through December 31, 2026, from CMS's Part B drug payment limit file. Multiply by the units billed for the allowed amount before deductible and coinsurance. It is not a coverage decision.
- What is one billing unit of J2300?
- One unit of J2300 is 10 mg, as stated in the code's descriptor. Units to report = dose given ÷ 10 mg. J-code billing units.