HCPCS drug code · CMS crosswalk
Naloxone HCl J-Code / HCPCS Code
In short
Naloxone HCl is billed under HCPCS J2312 — Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg. One billing unit is 0.01 mg. CMS's crosswalk lists 47 Naloxone HCl NDCs under this code.
Reference
- J2312
- Injection, naloxone hydrochloride, not otherwise specified, 0.01 mgBilling unit: 0.01 mg
- Labelers
- A-S Medication Solutions; Baxter Healthcare Corporation; Civica, Inc.; Dr. Reddy's Laboratories Inc.; Endo USA, Inc.; Eugia US LLC; FreseniUS Kabi USA, LLC; HF Acquisition Co. LLC, DBA HealthFirstand 7 more
Medicare Part B payment limit
CMS ASP filePayment limit per unit$0.076
Per0.01 mg
Coinsurance20%
Effective October 1, 2026 through December 31, 2026. Payment allowance limits subject to the ASP methodology are based on 2Q26 ASP data. A payment limit is not a coverage decision; the Medicare contractor decides coverage. CMS ASP pricing files
Naloxone HCl units and claim line
Enter the dose given to get the J2312 units and the NDC line for the CMS-1500 and the 837P.
Enter the dose given to build the claim line.
Naloxone HCl NDCs and billing units
From CMS’s ASP NDC–HCPCS crosswalk, effective October 1, 2026 through December 31, 2026. Billing units per package are CMS’s figures for the code’s unit.
| NDC (11-digit) | HCPCS | Labeler | Package | Billing units per package |
|---|---|---|---|---|
| 00404-9773-01 | J2312 | Henry Schein Inc. | 1 | 40 |
| 00404-9920-01 | J2312 | Henry Schein Inc. | 1 | 40 |
| 00404-9921-02 | J2312 | Henry Schein Inc. | 2 | 200 |
| 00404-9922-02 | J2312 | Henry Schein Inc. | 2 | 200 |
| 00404-9923-01 | J2312 | Henry Schein Inc. | 1 | 40 |
| 00409-1215-01 | J2312 | Pfizer Inc | 10 × 1 | 400 |
| 00409-1219-01 | J2312 | Pfizer Inc | 25 × 10 | 10000 |
| 00409-1782-69 | J2312 | Pfizer Inc | 10 × 1 | 400 |
| 00641-6132-25 | J2312 | Hikma Pharmaceuticals USA Inc. | 25 × 1 | 1000 |
| 00641-6193-10 | J2312 | Hikma Pharmaceuticals USA Inc. | 10 × 1 | 400 |
| 00641-6205-10 | J2312 | Hikma Pharmaceuticals USA Inc. | 10 × 2 | 4000 |
| 36000-0308-10 | J2312 | Baxter Healthcare Corporation | 10 × 1 | 400 |
| 36000-0310-02 | J2312 | Baxter Healthcare Corporation | 10 | 400 |
| 42023-0224-01 | J2312 | Endo USA, Inc. | 2 | 200 |
| 43066-0142-10 | J2312 | Baxter Healthcare Corporation | 10 × 2 | 2000 |
| 43598-0750-10 | J2312 | Dr. Reddy's Laboratories Inc. | 10 × 2 | 2000 |
| 43598-0750-58 | J2312 | Dr. Reddy's Laboratories Inc. | 10 × 2 | 2000 |
| 50090-3294-00 | J2312 | A-S Medication Solutions | 10 × 1 | 400 |
| 50090-5427-00 | J2312 | A-S Medication Solutions | 10 × 1 | 400 |
| 50090-6491-00 | J2312 | A-S Medication Solutions | 10 × 1 | 400 |
| 51662-1238-01 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 40 |
| 51662-1239-01 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 2 | 200 |
| 51662-1239-03 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 10 × 2 | 2000 |
| 51662-1242-01 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 1 | 40 |
| 51662-1242-03 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 50 × 1 | 2000 |
| 51662-1385-01 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 10 | 400 |
| 51662-1586-01 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 2 | 200 |
| 51662-1586-03 | J2312 | HF Acquisition Co. LLC, DBA HealthFirst | 10 × 2 | 2000 |
| 51662-1673-01 | J2312 | Henry Schein Inc. | 10 | 400 |
| 55150-0328-10 | J2312 | Eugia US LLC | 10 × 10 | 4000 |
| 55150-0345-10 | J2312 | Eugia US LLC | 10 × 2 | 2000 |
| 67457-0292-02 | J2312 | Mylan Institutional LLC | 10 × 1 | 400 |
| 67457-0299-10 | J2312 | Mylan Institutional LLC | 10 × 10 | 4000 |
| 67457-0599-02 | J2312 | Mylan Institutional LLC | 10 × 1 | 400 |
| 67457-0645-02 | J2312 | Mylan Institutional LLC | 10 × 1 | 400 |
| 67457-0987-10 | J2312 | Mylan Institutional LLC | 10 × 10 | 4000 |
| 67457-0992-02 | J2312 | Mylan Institutional LLC | 2 | 400 |
| 70069-0071-10 | J2312 | Somerset Pharma, LLC | 10 × 1 | 400 |
| 70069-0072-10 | J2312 | Somerset Pharma, LLC | 10 × 10 | 4000 |
| 70756-0658-10 | J2312 | Lifestar Pharma | 10 × 1 | 400 |
| 70756-0658-25 | J2312 | Lifestar Pharma | 25 × 1 | 1000 |
| 70756-0850-10 | J2312 | Lifestar Pharma | 10 × 1 | 400 |
| 72572-0450-25 | J2312 | Civica, Inc. | 25 × 1 | 1000 |
| 72603-0590-10 | J2312 | Northstar RxLLC | 10 × 1 | 400 |
| 72603-0590-25 | J2312 | Northstar RxLLC | 25 × 1 | 1000 |
| 76045-0112-20 | J2312 | FreseniUS Kabi USA, LLC | 24 × 2 | 4800 |
| 76045-0114-10 | J2312 | FreseniUS Kabi USA, LLC | 24 × 1 | 960 |
Naloxone HCl: common questions
- What is the J-code for Naloxone HCl?
- Naloxone HCl is billed under HCPCS J2312 — Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg. One billing unit is 0.01 mg. CMS's crosswalk lists 47 Naloxone HCl NDCs under this code.
- How many J2312 billing units are in a package of Naloxone HCl?
- CMS lists 40 to 10,000 billing units per package, depending on the NDC, where one unit is 0.01 mg. Units to report are based on the dose given, not the package.
- Is J2312 a CPT code?
- No. J2312 is a HCPCS Level II code from CMS for the drug itself. Giving it, for example by injection or infusion, is usually reported with a separate CPT administration code.